Genome-wide linkage analysis of blood pressure under locus heterogeneity.

Xinqun Yang, Kai Wang, Jian Huang, Veronica J. Vieland

Research output: Journal article publicationJournal articleAcademic researchpeer-review

6 Citations (Scopus)

Abstract

We describe a method for mapping quantitative trait loci that allows for locus heterogeneity. A genome-wide linkage analysis of blood pressure was performed using sib-pair data from the Framingham Heart Study. Evidence of linkage was found on four markers (GATA89G08, GATA23D06, GATA14E09, and 049xd2) at a significance level of 0.01. Two of them (GATA14E09 and 049xd2) seem to overlap with linkage signals reported previously, while the other two are not linked to any known signals.
Original languageEnglish
Article numberS78
JournalBMC Genetics
Volume4 Suppl 1
Publication statusPublished - 1 Dec 2003

ASJC Scopus subject areas

  • Genetics
  • Genetics(clinical)

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