Gallium and Functionalized-Porphyrins Combine to Form Potential Lysosome-Specific Multimodal Bioprobes

Jie Pan, Bethany I. Harriss, Chi Fai Chan, Lijun Jiang, Tik Hung Tsoi, Nicholas J. Long, Wing Tak Wong, Wai Kwok Wong, Ka Leung Wong

Research output: Journal article publicationJournal articleAcademic researchpeer-review

9 Citations (Scopus)

Abstract

A water-soluble bimetallic normal ("cold") and radiochemical ("hot") gallium-porphyrin-ruthenium-bipyridine complex (GaporRu-1) has been synthesized by microwave methodology in short reaction times with good (>85%) yields.68GaporRu-1 is demonstrated to be a potential multimodal and functional bioprobe for positron emission tomography (PET), lysosome specific optical imaging, and photodynamic therapy.
Original languageEnglish
Pages (from-to)6839-6841
Number of pages3
JournalInorganic Chemistry
Volume55
Issue number14
DOIs
Publication statusPublished - 18 Jul 2016

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Inorganic Chemistry

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