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FYCO1 regulates autophagy and senescence via PAK1/p21 in cataract
Shuying Chen
, Wei Zhao
, Rongrong Chen
, Feiyin Sheng
, Yuzhou Gu
, Shengjie Hao
, Di Wu
, Bing Lu
, Lu Chen
, Yuhao Wu
, Yili Xu
, Yu Han
,
Lei Zhou
, S. Amer Riazuddin
, Qiuli Fu (Corresponding Author)
, Ke Yao (Corresponding Author)
School of Optometry
The Hong Kong Polytechnic University
Department of Applied Biology and Chemical Technology
Research output
:
Journal article publication
›
Journal article
›
Academic research
›
peer-review
7
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Citations (Scopus)
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Dive into the research topics of 'FYCO1 regulates autophagy and senescence via PAK1/p21 in cataract'. Together they form a unique fingerprint.
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Keyphrases
Cataract
100%
Senescence
100%
PAK1
100%
Autophagy
100%
FYCO1
100%
Ultraviolet-B (UV-B)
33%
Human Lens Epithelial Cells
33%
Hydrogen Peroxide
11%
Western Blot
11%
β-Galactosidase (β-Gal)
11%
Protein Expression
11%
Gene Expression
11%
Quantitative PCR
11%
Mouse Model
11%
Structural Damage
11%
Coiled-coil Domain
11%
Oxidative Stress
11%
Hematoxylin
11%
Eosin
11%
Cell Response
11%
Blindness
11%
Vision Impairment
11%
Basal Autophagy
11%
Immunofluorescence Staining
11%
Cell Autophagy
11%
Senescence-associated
11%
Age-related Cataract
11%
Cell Counting kit-8 (CCK-8)
11%
H2O2 Treatment
11%
Lens Epithelial Cells
11%
UVB Irradiation
11%
Cataractogenesis
11%
Autophagy Adaptors
11%
Lens Morphology
11%
Medicine and Dentistry
Autophagy
100%
Cataract
100%
P21
100%
P21 Activated Kinase 1
100%
Epithelial Cell
66%
Hydrogen Peroxide
33%
In Vitro
16%
Oxidative Stress
16%
Visual Impairment
16%
down Regulation
16%
Gene Expression
16%
Haematoxylin
16%
Eosin
16%
Protein Expression
16%
Western Blot
16%
Cataractogenesis
16%
Cell Counting
16%
Real-Time Polymerase Chain Reaction
16%
Senile Cataract
16%
Immunofluorescence
16%
Galactosidase
16%
Biochemistry, Genetics and Molecular Biology
P21-Activated Kinases
100%
P21
100%
Autophagy
100%
Hydrogen Peroxide
40%
Immunofluorescence
20%
Mouse Model
20%
Coiled Coil
20%
Western Blot
20%
Oxidative Stress
20%
Gene Expression
20%
Real-Time Polymerase Chain Reaction
20%
Protein Expression
20%
down Regulation
20%
Eosin
20%
Galactosidase
20%