Formation of nanoliter bubbles in microfluidic T-junctions

Jing Fan; Yuxiang Zhang; Liqiu Wang

doi:10.1142/S1793292010002086

Formation of nanoliter bubbles in microfluidic T-junctions

Jing Fan, Yuxiang Zhang, Liqiu Wang

Research output: Journal article publication › Journal article › Academic research › peer-review

4 Citations (Scopus)

Abstract

A numerical study on nanoliter bubble formation process in microfluidic T-junctions is conducted. The simulated bubble sequence agrees well with experiments. The pressure and velocity distribution in liquid phase, and streamlines of relative velocity of liquid to bubbles are obtained. We also studied pressure variation at the junction and gas flow rate for the first several bubbles, and illustrated the special impact of channel width ratio on bubble formation process. Finally, we derived the critical nondimensional gas pressure above which bubbles can be generated.

Original language	English
Pages (from-to)	175-184
Number of pages	10
Journal	Nano
Volume	5
Issue number	3
DOIs	https://doi.org/10.1142/S1793292010002086
Publication status	Published - Jun 2010
Externally published	Yes

Keywords

Microfluidic T-junction
nanoliter bubble formation
numerical simulation
two-phase flow

ASJC Scopus subject areas

General Materials Science
Condensed Matter Physics

More information

10.1142/S1793292010002086

Cite this

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title = "Formation of nanoliter bubbles in microfluidic T-junctions",

abstract = "A numerical study on nanoliter bubble formation process in microfluidic T-junctions is conducted. The simulated bubble sequence agrees well with experiments. The pressure and velocity distribution in liquid phase, and streamlines of relative velocity of liquid to bubbles are obtained. We also studied pressure variation at the junction and gas flow rate for the first several bubbles, and illustrated the special impact of channel width ratio on bubble formation process. Finally, we derived the critical nondimensional gas pressure above which bubbles can be generated.",

keywords = "Microfluidic T-junction, nanoliter bubble formation, numerical simulation, two-phase flow",

author = "Jing Fan and Yuxiang Zhang and Liqiu Wang",

note = "Funding Information: The financial support from the Research Grants Council of Hong Kong (GRF718009) and the CRCG of the University of Hong Kong (200707176111) is gratefully acknowledged.",

year = "2010",

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doi = "10.1142/S1793292010002086",

language = "English",

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TY - JOUR

T1 - Formation of nanoliter bubbles in microfluidic T-junctions

AU - Fan, Jing

AU - Zhang, Yuxiang

AU - Wang, Liqiu

N1 - Funding Information: The financial support from the Research Grants Council of Hong Kong (GRF718009) and the CRCG of the University of Hong Kong (200707176111) is gratefully acknowledged.

PY - 2010/6

Y1 - 2010/6

N2 - A numerical study on nanoliter bubble formation process in microfluidic T-junctions is conducted. The simulated bubble sequence agrees well with experiments. The pressure and velocity distribution in liquid phase, and streamlines of relative velocity of liquid to bubbles are obtained. We also studied pressure variation at the junction and gas flow rate for the first several bubbles, and illustrated the special impact of channel width ratio on bubble formation process. Finally, we derived the critical nondimensional gas pressure above which bubbles can be generated.

AB - A numerical study on nanoliter bubble formation process in microfluidic T-junctions is conducted. The simulated bubble sequence agrees well with experiments. The pressure and velocity distribution in liquid phase, and streamlines of relative velocity of liquid to bubbles are obtained. We also studied pressure variation at the junction and gas flow rate for the first several bubbles, and illustrated the special impact of channel width ratio on bubble formation process. Finally, we derived the critical nondimensional gas pressure above which bubbles can be generated.

KW - Microfluidic T-junction

KW - nanoliter bubble formation

KW - numerical simulation

KW - two-phase flow

UR - http://www.scopus.com/inward/record.url?scp=78649509612&partnerID=8YFLogxK

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DO - 10.1142/S1793292010002086

M3 - Journal article

AN - SCOPUS:78649509612

SN - 1793-2920

VL - 5

SP - 175

EP - 184

JO - Nano

JF - Nano

IS - 3

ER -

Formation of nanoliter bubbles in microfluidic T-junctions

Abstract

Keywords

ASJC Scopus subject areas

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