Formation of nanoliter bubbles in microfluidic T-junctions

Jing Fan, Yuxiang Zhang, Liqiu Wang

Research output: Journal article publicationJournal articleAcademic researchpeer-review

4 Citations (Scopus)


A numerical study on nanoliter bubble formation process in microfluidic T-junctions is conducted. The simulated bubble sequence agrees well with experiments. The pressure and velocity distribution in liquid phase, and streamlines of relative velocity of liquid to bubbles are obtained. We also studied pressure variation at the junction and gas flow rate for the first several bubbles, and illustrated the special impact of channel width ratio on bubble formation process. Finally, we derived the critical nondimensional gas pressure above which bubbles can be generated.

Original languageEnglish
Pages (from-to)175-184
Number of pages10
Issue number3
Publication statusPublished - Jun 2010
Externally publishedYes


  • Microfluidic T-junction
  • nanoliter bubble formation
  • numerical simulation
  • two-phase flow

ASJC Scopus subject areas

  • General Materials Science
  • Condensed Matter Physics


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