Abstract
Wavefront distortion in scattering media can be compensated for using optical wavefront shaping. In this technique, a spatial light modulator (SLM) is used to apply a spatially distributed phase shift to the optical field. A genetic optimization algorithm was used to obtain the SLM pattern which best focuses light within the medium. The target volume is defined by using a focused ultrasound beam to encode light travelling within the acoustic focus. The ultrasonically-encoded light is measured and used as feedback to the algorithm, which then searches for the pattern which maximizes the encoded light intensity. We call this technique ultrasonically-encoded wavefront shaping (SEWS). Using SEWS, we focused light into a scattering medium consisting of ground glass diffuser and a gelatin phantom. The optical intensity at the target was increased by 11 times over the original intensity. These results were validated using fluorescent imaging at the ultrasonic focus.
Original language | English |
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Title of host publication | Photons Plus Ultrasound |
Subtitle of host publication | Imaging and Sensing 2014 |
Publisher | SPIE |
Volume | 8943 |
ISBN (Print) | 9780819498564 |
DOIs | |
Publication status | Published - 1 Jan 2014 |
Externally published | Yes |
Event | Photons Plus Ultrasound: Imaging and Sensing 2014 - San Francisco, CA, United States Duration: 2 Feb 2014 → 5 Feb 2014 |
Conference
Conference | Photons Plus Ultrasound: Imaging and Sensing 2014 |
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Country/Territory | United States |
City | San Francisco, CA |
Period | 2/02/14 → 5/02/14 |
Keywords
- Imaging
- Optical Engineering
- Spatial Light Modulator
- Turbidity Compensation
- Ultrasound
- Wavefront Shaping
ASJC Scopus subject areas
- Atomic and Molecular Physics, and Optics
- Electronic, Optical and Magnetic Materials
- Biomaterials
- Radiology Nuclear Medicine and imaging