Abstract
(±)-epi-Conocarpan 1 was synthesized via the key intermediate 5-bromo-cis-2-(4-methoxyphenyl)-3-methyl-2,3-dihydrobenzofuran 6 which was synthesized by a ruthenium(II) porphyrin-catalyzed intramolecular C-H insertion reaction using aryl tosylhydrazone salt 5 as the carbene source, starting from the commercially available 5-bromo-2-hydroxyacetophenone.
Original language | English |
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Pages (from-to) | 1445-1447 |
Number of pages | 3 |
Journal | Tetrahedron Letters |
Volume | 44 |
Issue number | 7 |
DOIs | |
Publication status | Published - 10 Feb 2003 |
Keywords
- (±)-epi-conocarpan
- cis-2,3-dihydrobenzofuran
- Intramolecular C-H insertion
- Ruthenium(II) porphyrin
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry