Factors associated with atopy in toddlers: A case-control study

Jolene Yung, Wai Man Yuen, Yvonne Ou, Jean Tak Alice Loke Yuen

Research output: Journal article publicationJournal articleAcademic researchpeer-review

3 Citations (Scopus)


In this case-control study the association between the approaches used to feed infants, together with known family and environmental factors, and the occurrence of atopic illness in toddlers between the ages of 4 months to 3 years in Hong Kong was examined. A total of 206 subjects were recruited from April to June of 2014. The results obtained by binary logistic regression indicated that atopy is associated with boys (OR 2.072, CI 1.089–3.941), the maternal use of antibiotics in utero or while breast feeding (OR 2.276, CI 1.151–4.504), the later commencement of mixed feeding (OR 2.497, CI 1.025–6.082), breast feeding exclusively for 3 months (OR 1.972, CI 1.009–3.857), and having a mother who was diagnosed with eczema (OR 4.510, CI 1.764–11.530). Although an exclusive reliance on breast feeding has been shown to be predictive of atopy among toddlers, the positive qualities of breast milk cannot be ignored. A further study of the contents and nutritional values of breast milk is warranted.
Original languageEnglish
Pages (from-to)2501-2520
Number of pages20
JournalInternational Journal of Environmental Research and Public Health
Issue number3
Publication statusPublished - 25 Feb 2015


  • Atopy
  • Breast-feeding
  • Maternal antibiotic use
  • Toddlers

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Health, Toxicology and Mutagenesis


Dive into the research topics of 'Factors associated with atopy in toddlers: A case-control study'. Together they form a unique fingerprint.

Cite this