Fabrication of organic electrochemical transistor arrays for biosensing

Meng Zhang, Peng Lin, Mo Yang, Feng Yan

Research output: Journal article publicationJournal articleAcademic researchpeer-review

21 Citations (Scopus)

Abstract

Background: Organic electrochemical transistors (OECT) have been used as various types of biosensors with very high sensitivity. The OECTs show advantages of easy fabrication, low operational voltage, excellent flexibility and biocompatibility. Methods: OECT arrays based on poly(3,4- ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS) were fabricated in poly(ethylene glycol) (PEG) microwells by physical delamination. Results: The OECTs show fast response time, stable channel current and excellent transistor characteristics. The PEG microwells can be used to trap cells on top of the OECTs, which will be important for the application of the OECT arrays as cell-based biosensors. General significance: This technique provides a feasible way for high-throughput cell analysis based on transistor arrays. This article is part of a Special Issue entitled Organic Bioelectronics - Novel Applications in Biomedicine.
Original languageEnglish
Pages (from-to)4402-4406
Number of pages5
JournalBiochimica et Biophysica Acta - General Subjects
Volume1830
Issue number9
DOIs
Publication statusPublished - 1 Jan 2013

Keywords

  • Cell-based biosensor
  • Microarray
  • Organic thin film transistor

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology

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