Abstract
This paper presents a new stochastic-based method for modelling and analysis of COVID-19 spread. A new deterministic Susceptible, Exposed, Infectious, Recovered (Re-infected) and Deceased-based Social Distancing model, named SEIR(R)D-SD, is proposed by introducing the re-infection rate and social distancing factor into the traditional SEIRD (Susceptible, Exposed, Infectious, Recovered and Deceased) model to account for the effects of re-infection and social distancing on COVID-19 spread. The deterministic SEIRD(R)D-SD model is further converted into the stochastic form to account for uncertainties involved in COVID-19 spread. Based on this, an extended Kalman filter (EKF) is developed based on the stochastic SEIR(R)D-SD model to simultaneously estimate both model parameters and transmission state of COVID-19 spread. Simulation results and comparison analyses demonstrate that the proposed method can effectively account for the re-infection and social distancing as well as uncertain effects on COVID-19 spread, leading to improved accuracy for prediction of COVID-19 spread.
| Original language | English |
|---|---|
| Article number | 104810 |
| Journal | Computers in Biology and Medicine |
| Volume | 137 |
| DOIs | |
| Publication status | Published - Oct 2021 |
Keywords
- And extended kalman filter
- COVID-19 modelling
- Re-infection
- Social distancing
- Stochastic epidemiological model
ASJC Scopus subject areas
- Computer Science Applications
- Health Informatics