Expression of Hex mRNA in early murine postimplantation embryo development

Wee-Keong Vincent Keng; Kazuhiro E. Fujimori; Zaw Myint; Nobuaki Tamamaki; Yoshiaki Nojyo; Tamio Noguchi

doi:10.1016/S0014-5793(98)00342-1

Expression of Hex mRNA in early murine postimplantation embryo development

Wee-Keong Vincent Keng, Kazuhiro E. Fujimori, Zaw Myint, Nobuaki Tamamaki, Yoshiaki Nojyo, Tamio Noguchi

Research output: Journal article publication › Journal article › Academic research › peer-review

48 Citations (Scopus)

Abstract

The onset of Hex expression and its role in early murine development was analyzed using in situ hybridization. Hex mRNA was first detected in the chorion of the ectoplacental cavity and weakly at the visceral endoderm of the future yolk sac at embryonic age (E) 7.5. Expression in embryonic tissues was detected exclusively in the hepatic anlage and thyroid primordium at E 9.5. At E 12.5 and E 15.5, Hex expression persisted in the fetal liver and thyroid, and was also detected in the fetal lung. These results suggest that Hex has its role in differentiation and/or organogenesis of several embryonic tissues.

Original language	English
Pages (from-to)	183-186
Number of pages	4
Journal	FEBS Letters
Volume	426
Issue number	2
DOIs	https://doi.org/10.1016/S0014-5793(98)00342-1
Publication status	Published - 17 Apr 1998
Externally published	Yes

Keywords

Hex
In situ hybridization
Liver
Lung
Murine embryo
Thyroid

ASJC Scopus subject areas

Biochemistry
Biophysics
Molecular Biology

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10.1016/S0014-5793(98)00342-1

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title = "Expression of Hex mRNA in early murine postimplantation embryo development",

abstract = "The onset of Hex expression and its role in early murine development was analyzed using in situ hybridization. Hex mRNA was first detected in the chorion of the ectoplacental cavity and weakly at the visceral endoderm of the future yolk sac at embryonic age (E) 7.5. Expression in embryonic tissues was detected exclusively in the hepatic anlage and thyroid primordium at E 9.5. At E 12.5 and E 15.5, Hex expression persisted in the fetal liver and thyroid, and was also detected in the fetal lung. These results suggest that Hex has its role in differentiation and/or organogenesis of several embryonic tissues.",

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T1 - Expression of Hex mRNA in early murine postimplantation embryo development

AU - Keng, Wee-Keong Vincent

AU - Fujimori, Kazuhiro E.

AU - Myint, Zaw

AU - Tamamaki, Nobuaki

AU - Nojyo, Yoshiaki

AU - Noguchi, Tamio

PY - 1998/4/17

Y1 - 1998/4/17

N2 - The onset of Hex expression and its role in early murine development was analyzed using in situ hybridization. Hex mRNA was first detected in the chorion of the ectoplacental cavity and weakly at the visceral endoderm of the future yolk sac at embryonic age (E) 7.5. Expression in embryonic tissues was detected exclusively in the hepatic anlage and thyroid primordium at E 9.5. At E 12.5 and E 15.5, Hex expression persisted in the fetal liver and thyroid, and was also detected in the fetal lung. These results suggest that Hex has its role in differentiation and/or organogenesis of several embryonic tissues.

AB - The onset of Hex expression and its role in early murine development was analyzed using in situ hybridization. Hex mRNA was first detected in the chorion of the ectoplacental cavity and weakly at the visceral endoderm of the future yolk sac at embryonic age (E) 7.5. Expression in embryonic tissues was detected exclusively in the hepatic anlage and thyroid primordium at E 9.5. At E 12.5 and E 15.5, Hex expression persisted in the fetal liver and thyroid, and was also detected in the fetal lung. These results suggest that Hex has its role in differentiation and/or organogenesis of several embryonic tissues.

KW - Hex

KW - In situ hybridization

KW - Liver

KW - Lung

KW - Murine embryo

KW - Thyroid

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DO - 10.1016/S0014-5793(98)00342-1

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JO - FEBS Letters

JF - FEBS Letters

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Expression of Hex mRNA in early murine postimplantation embryo development

Abstract

Keywords

ASJC Scopus subject areas

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