Experimental spinal cord injury and behavioral tests in laboratory rats

Rakib Uddin Ahmed; Monzurul Alam; Yong Ping Zheng

doi:10.1016/j.heliyon.2019.e01324

Experimental spinal cord injury and behavioral tests in laboratory rats

Rakib Uddin Ahmed, Monzurul Alam, Yong Ping Zheng

Research output: Journal article publication › Review article › Academic research › peer-review

35 Citations (Scopus)

Abstract

Traumatic spinal cord injury (SCI) results in some serious neurophysiological consequences that alter healthy body functions and devastate the quality of living of individuals. To find a cure for SCI, researchers around the world are working on different neurorepair and neurorehabilitation modalities. To test a new treatment for SCI as well as to understand the mechanism of recovery, animal models are being widely used. Among them, SCI rat models are arguably the most prominent. Furthermore, it is important to select a suitable behavioral test to evaluate both the motor and sensory recovery following any therapeutic intervention. In this paper, we review the rat models of spinal injury and commonly used behavioral tests to serve as a useful guideline for neuroscientists in the field of SCI research.

Original language	English
Article number	e01324
Journal	Heliyon
Volume	5
Issue number	3
DOIs	https://doi.org/10.1016/j.heliyon.2019.e01324
Publication status	Published - Mar 2019

Keywords

Anatomy
Neurology
Neuroscience
Physiology
Rehabilitation
Surgery

ASJC Scopus subject areas

General

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10.1016/j.heliyon.2019.e01324

http://hdl.handle.net/10397/80740

Cite this

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Experimental spinal cord injury and behavioral tests in laboratory rats

Abstract

Keywords

ASJC Scopus subject areas

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