Experimental assessment of the performance of vitreous cutters with fluids with different rheological properties

Irene Nepita, Rodolfo Repetto, Andrea Dodero, Silvia Vicini, Mariantonia Ferrara, Mario R. Romano, Alessandro Stocchino

Research output: Journal article publicationJournal articleAcademic researchpeer-review

3 Citations (Scopus)


Purpose: To assess the influence of rheological properties of an artificial vitreous (AV) on the performance of double-blade (DB) and single-blade (SB) guillotine vitreous cutters, with 23-, 25-, and 27-gauge (G) probes. Methods: We evaluate the aspiration flow rate, using an optical method, based on image processing. Experiments are conducted using ten viscoelastic vitreous phantoms, with different properties that are measured with rheological tests. Results: Aspiration rate strongly varies with fluid properties. Regardless of cutter geometry and operational conditions, the flow rate significantly decreases as vitreous viscosity and elasticity increase. Conclusions: All tested vitreous probes are very sensitive to changes in fluid rheology. SB cutters produce smaller flow rates compared with DB ones of the same caliber; however, they are less sensitive to fluid properties at low aspiration pressures. The use of vitreous substitutes for test performance guarantees comparability between flow rate results achieved with different vitrectomy systems operating in different media. This outcome is further confirmed by the low values of estimated flow rate relative errors. [Figure not available: see fulltext.].

Original languageEnglish
Pages (from-to)1113-1121
Number of pages9
JournalGraefe's Archive for Clinical and Experimental Ophthalmology
Issue number5
Publication statusPublished - May 2021


  • Artificial vitreous
  • Flow rate measurements
  • Rheological properties
  • Vitrectomy

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience


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