TY - JOUR
T1 - Evaluation of anti-oxidant capacity of root of scutellaria baicalensis georgi, in comparison with roots of polygonum multiflorum thunb and panax ginseng CA meyer
AU - Chan, Enoch
AU - Wong, Cynthia Ying Kat
AU - Wan, Chun Wai
AU - Kwok, Ching Yee
AU - Wu, Jian Hong
AU - Ng, Kar Man
AU - So, Chi Hang
AU - Au, Alice Lai Shan
AU - Poon, Christina Chui Wa
AU - Seto, Sai Wang
AU - Kwan, Yiu Wa
AU - Yu, Peter Hoi Fu
AU - Chan, Shun Wan
N1 - Funding Information:
This research project was partly supported by a grant from the Shenzhen Government and the Niche Area Research Grant from the Hong Kong Polytechnic University (Hong Kong SAR, PR China). The authors would also like to thank Siu-Hung Tsui for proof-reading the manuscript.
Copyright:
Copyright 2011 Elsevier B.V., All rights reserved.
PY - 2010
Y1 - 2010
N2 - In Chinese communities, regular consumption of Chinese-medicated diets (CMD) (usually in the form of soup) is a traditional practice to promote health and prevent disease development. The overall improvement of health conditions is believed to be correlated with the anti-oxidant potentials of these herbs. Huangqin, roots of Scutellaria baicalensis Georgi (Lamiaceae), is one of the herbs commonly used in CMD. In this study, the anti-oxidant capacities of Huangqin extracts (water, ethanol and ether extracts) were evaluated and compared to commonly used CMD herbs, Heshouwu, roots of Polygonum multiflorum Thunb (Polygonaceae) and Renshen (or Ginseng), roots of Panax ginseng CA Meyer (Araliaceae). The anti-oxidant capacities were measured by using both cell-free assay [ferric reducing/anti-oxidant power (FRAP)] and biological methods [2,2'-azobis(2-amidinopropane) (AAPH)-induced haemolysis assay and H 2O2-induced cell damage on H9C2 cells]. Additionally, the total phenolic content was measured using Folin-Ciocalteu methods. Water extract of Huangqin has the highest anti-oxidant activities compared to the ethanol and ether extracts. A positive relationship between the anti-oxidant effects and total phenolic contents of extracts was demonstrated. This shows that Huangqin could be an effective dietary anti-oxidant that can be consumed regularly as a functional food for the prevention of oxidant/free radical-related diseases.
AB - In Chinese communities, regular consumption of Chinese-medicated diets (CMD) (usually in the form of soup) is a traditional practice to promote health and prevent disease development. The overall improvement of health conditions is believed to be correlated with the anti-oxidant potentials of these herbs. Huangqin, roots of Scutellaria baicalensis Georgi (Lamiaceae), is one of the herbs commonly used in CMD. In this study, the anti-oxidant capacities of Huangqin extracts (water, ethanol and ether extracts) were evaluated and compared to commonly used CMD herbs, Heshouwu, roots of Polygonum multiflorum Thunb (Polygonaceae) and Renshen (or Ginseng), roots of Panax ginseng CA Meyer (Araliaceae). The anti-oxidant capacities were measured by using both cell-free assay [ferric reducing/anti-oxidant power (FRAP)] and biological methods [2,2'-azobis(2-amidinopropane) (AAPH)-induced haemolysis assay and H 2O2-induced cell damage on H9C2 cells]. Additionally, the total phenolic content was measured using Folin-Ciocalteu methods. Water extract of Huangqin has the highest anti-oxidant activities compared to the ethanol and ether extracts. A positive relationship between the anti-oxidant effects and total phenolic contents of extracts was demonstrated. This shows that Huangqin could be an effective dietary anti-oxidant that can be consumed regularly as a functional food for the prevention of oxidant/free radical-related diseases.
KW - Anti-Oxidant Activity
KW - Chinese-Medicated Diet
KW - Ferric Reducing/Anti-Oxidant Power (FRAP)
KW - Panax ginseng CA Meyer
KW - Polygonum multiflorum Thunb
KW - Scutellaria baicalensis Georgi
KW - Total Phenol Content
UR - http://www.scopus.com/inward/record.url?scp=77954601903&partnerID=8YFLogxK
U2 - 10.1142/S0192415X10008263
DO - 10.1142/S0192415X10008263
M3 - Journal article
C2 - 20626065
AN - SCOPUS:77954601903
SN - 0192-415X
VL - 38
SP - 815
EP - 827
JO - American Journal of Chinese Medicine
JF - American Journal of Chinese Medicine
IS - 4
ER -