Evaluation of anti-oxidant capacity of root of scutellaria baicalensis georgi, in comparison with roots of polygonum multiflorum thunb and panax ginseng CA meyer

Enoch Chan, Cynthia Ying Kat Wong, Chun Wai Wan, Ching Yee Kwok, Jian Hong Wu, Kar Man Ng, Chi Hang So, Alice Lai Shan Au, Christina Chui Wa Poon, Sai Wang Seto, Yiu Wa Kwan, Peter Hoi Fu Yu, Shun Wan Chan

Research output: Journal article publicationJournal articleAcademic researchpeer-review

44 Citations (Scopus)

Abstract

In Chinese communities, regular consumption of Chinese-medicated diets (CMD) (usually in the form of soup) is a traditional practice to promote health and prevent disease development. The overall improvement of health conditions is believed to be correlated with the anti-oxidant potentials of these herbs. Huangqin, roots of Scutellaria baicalensis Georgi (Lamiaceae), is one of the herbs commonly used in CMD. In this study, the anti-oxidant capacities of Huangqin extracts (water, ethanol and ether extracts) were evaluated and compared to commonly used CMD herbs, Heshouwu, roots of Polygonum multiflorum Thunb (Polygonaceae) and Renshen (or Ginseng), roots of Panax ginseng CA Meyer (Araliaceae). The anti-oxidant capacities were measured by using both cell-free assay [ferric reducing/anti-oxidant power (FRAP)] and biological methods [2,2'-azobis(2-amidinopropane) (AAPH)-induced haemolysis assay and H 2O2-induced cell damage on H9C2 cells]. Additionally, the total phenolic content was measured using Folin-Ciocalteu methods. Water extract of Huangqin has the highest anti-oxidant activities compared to the ethanol and ether extracts. A positive relationship between the anti-oxidant effects and total phenolic contents of extracts was demonstrated. This shows that Huangqin could be an effective dietary anti-oxidant that can be consumed regularly as a functional food for the prevention of oxidant/free radical-related diseases.

Original languageEnglish
Pages (from-to)815-827
Number of pages13
JournalAmerican Journal of Chinese Medicine
Volume38
Issue number4
DOIs
Publication statusPublished - 2010

Keywords

  • Anti-Oxidant Activity
  • Chinese-Medicated Diet
  • Ferric Reducing/Anti-Oxidant Power (FRAP)
  • Panax ginseng CA Meyer
  • Polygonum multiflorum Thunb
  • Scutellaria baicalensis Georgi
  • Total Phenol Content

ASJC Scopus subject areas

  • Complementary and alternative medicine

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