Epoxide ring opening catalysed by imidochromium complexes

Wa Hung Leung, Man Ching Wu, Joyce L.C. Chim, Man Tat Yu, Hong Wei Hou, Lam Lung Yeung, Wing Tak Wong, Yu Wang

Research output: Journal article publicationJournal articleAcademic researchpeer-review

7 Citations (Scopus)


tert-Butylimidochromium complexes catalysed ring opening of epoxides by SiMe3(N3) to give azidohydrins in good yields. The proposed mechanism for the chromium-mediated epoxide azidolysis involves the intermediacy of a chromium-azide species which delivers nucleophilic azide to the epoxide substrate. The azido complexes [{Cr(NBut)2Cl}2(μ-N3)2] 1 and [Cr(ButN=NN=NSiMe3)(N3)Cl2] 2 have been isolated in the reactions of SiMe3(N3) with [Cr(NBut)2Cl2] and [Cr(NBut)Cl3(dme)] (dme = 1,2-dimethoxyethane), respectively. The structure of complex 1 has been established by X-ray crystallography. The mean Cr-N (imide) and Cr-N (azide) distances are 1.605 and 2.061 Å, respectively. Reaction of [Cr(NBut)Cl3(thf)2] (thf = tetrahydrofuran) with (S,S)-diop {4,5-[bis(diphenylphosphino)methyl]-2,2-dimethyl-1,3-dioxolane} gave the dimeric complex [{Cr(NBut)Cl3}2{μ(S,S)-diop}], which has been characterised by X-ray crystallography. The Cr-N and Cr-P distances are 1.593(9) and 2.449(4) Å, respectively.
Original languageEnglish
Pages (from-to)3525-3529
Number of pages5
JournalJournal of the Chemical Society - Dalton Transactions
Issue number19
Publication statusPublished - 7 Oct 1997
Externally publishedYes

ASJC Scopus subject areas

  • Chemistry(all)


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