Enhanced Sensitivity of Surface Plasmon Resonance Phase-Interrogation Biosensor by Using Silver Nanoparticles

T.-C. Peng, W.-C. Lin, C.-W. Chen, Din-ping Tsai, H.-P. Chiang

Research output: Journal article publicationJournal articleAcademic researchpeer-review

35 Citations (Scopus)


It is demonstrated that the sensitivity of surface plasmon resonance phase-interrogation biosensor can be enhanced by using silver nanoparticles. Silver nanoparticles were fabricated on silver films by using thermal evaporation. Sizes of silver nanoparticles on silver thin film can be tuned by controlling the deposition parameters of thermal evaporation. By using surface plasmon resonance heterodyne interferometey to measure the phase difference between the p and s polarization of incident light, we have demonstrated that sensitivity of glucose detection down to the order of 10-8 refractive index units can be obtained. © 2010 Springer Science+Business Media, LLC.
Original languageEnglish
Pages (from-to)29-34
Number of pages6
Issue number1
Publication statusPublished - 1 Mar 2011
Externally publishedYes


  • Biosensor
  • Phase measurement
  • Silver nanoparticles
  • Surface plasmons

ASJC Scopus subject areas

  • Biotechnology
  • Biophysics
  • Biochemistry

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