Endothelin-1 induces chondrocyte senescence and cartilage damage via endothelin receptor type B in a post-traumatic osteoarthritis mouse model

Medicine and Dentistry

• Endothelin 1 100%
• Chondrocyte 81%
• Senescence 63%
• Osteoarthritis 45%
• Receptor 45%
• Endothelin 27%
• Development 27%
• Cartilage 27%
• In Vitro 18%
• Cartilage Degeneration 18%
• Surgery 18%
• Endothelin Receptor 18%
• Bone 18%
• Articular Cartilage 9%
• Ascorbic Acid 9%
• Synovial Membrane 9%
• Hydrogen Peroxide 9%
• Scavenger 9%
• Receptor Blocking 9%
• Mitochondrial Dynamics 9%
• Plasma 9%

Biochemistry, Genetics and Molecular Biology

• Endothelin 1 100%
• Senescence 63%
• Endothelin Receptor Type B 36%
• Mouse Model 27%
• Development 27%
• Degradation 18%
• Time 18%
• Transgenics 18%
• Scavenger 9%
• Receptor Blocking 9%
• Mitochondrial Dynamics 9%
• Species 9%
• Mouse 9%
• Vitamin C 9%
• Endothelin Receptor 9%

Pharmacology, Toxicology and Pharmaceutical Science

• Endothelin 1 100%
• Osteoarthritis 45%
• Receptor 45%
• Mouse Model 27%
• Endothelin 27%
• Cartilage Degeneration 18%
• Endothelin Receptor 18%
• Reactive Oxygen Metabolite 9%
• Hydrogen Peroxide 9%
• Ascorbic Acid 9%
• Scavenger 9%
• Vasoconstrictor Agent 9%
• Mouse 9%