Enantioselective synthesis of a taxol C ring

Cong Ma, Stéphanie Schiltz, Joëlle Prunet

Research output: Journal article publicationJournal articleAcademic researchpeer-review

5 Citations (Scopus)

Abstract

An enantioselective synthesis of a C ring of taxol has been accomplished. The key step is an oxidative cleavage of a derivative of the Wieland-Miescher ketone. A first attempt of a Shapiro reaction modelling the coupling of the C ring with the A fragment of taxol was also successful.
Original languageEnglish
Pages (from-to)1579-1594
Number of pages16
JournalCollection of Czechoslovak Chemical Communications
Volume76
Issue number12
DOIs
Publication statusPublished - 1 Dec 2011
Externally publishedYes

Keywords

  • Ozonolysis
  • Shapiro reaction
  • Synthesis design
  • Taxol
  • Terpenoids
  • Wieland-Miescher ketone

ASJC Scopus subject areas

  • Chemistry(all)

Cite this