Emerging role of fatty acid binding proteins in cancer pathogenesis

Shilpa Gurung; Katherine Po Sin Chung; Terence Kin Wah Lee

doi:10.14670/HH-18-014

Emerging role of fatty acid binding proteins in cancer pathogenesis

Shilpa Gurung, Katherine Po Sin Chung, Terence Kin Wah Lee

Research output: Journal article publication › Review article › Academic research › peer-review

4 Citations (Scopus)

Abstract

Fatty acid binding proteins (FABPs) are 15-kDa proteins responsible for the transport of fatty acids both intracellularly and extracellularly. Consisting of 12 different isoforms, some of the proteins have been found to be released in the serum and to be correlated with various diseases including cancer. Differential expression of these proteins has been reported to result in cancer pathogenesis by modulating various cancer signaling pathways; hence, in this review, we present the recent studies that have investigated the roles of different kinds of FABPs in different types of cancer and any possible underlying mechanisms to better understand the role of FABPs in cancer progression.

Original language	English
Pages (from-to)	1-12
Number of pages	12
Journal	Histology and Histopathology
Volume	34
Issue number	1
DOIs	https://doi.org/10.14670/HH-18-014
Publication status	Published - 1 Jan 2018

Keywords

Adipocytes
Cancer
Drug resistance
FABPs
Metastasis

ASJC Scopus subject areas

Pathology and Forensic Medicine
Histology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

More information

10.14670/HH-18-014

http://hdl.handle.net/10397/101573

Cite this

@article{43e70fd0210546df828fb9efd8ec2175,

title = "Emerging role of fatty acid binding proteins in cancer pathogenesis",

abstract = "Fatty acid binding proteins (FABPs) are 15-kDa proteins responsible for the transport of fatty acids both intracellularly and extracellularly. Consisting of 12 different isoforms, some of the proteins have been found to be released in the serum and to be correlated with various diseases including cancer. Differential expression of these proteins has been reported to result in cancer pathogenesis by modulating various cancer signaling pathways; hence, in this review, we present the recent studies that have investigated the roles of different kinds of FABPs in different types of cancer and any possible underlying mechanisms to better understand the role of FABPs in cancer progression.",

keywords = "Adipocytes, Cancer, Drug resistance, FABPs, Metastasis",

author = "Shilpa Gurung and Chung, {Katherine Po Sin} and Lee, {Terence Kin Wah}",

year = "2018",

month = jan,

day = "1",

doi = "10.14670/HH-18-014",

language = "English",

volume = "34",

pages = "1--12",

journal = "Histology and Histopathology",

issn = "0213-3911",

publisher = "Histology and Histopathology",

number = "1",

}

TY - JOUR

T1 - Emerging role of fatty acid binding proteins in cancer pathogenesis

AU - Gurung, Shilpa

AU - Chung, Katherine Po Sin

AU - Lee, Terence Kin Wah

PY - 2018/1/1

Y1 - 2018/1/1

N2 - Fatty acid binding proteins (FABPs) are 15-kDa proteins responsible for the transport of fatty acids both intracellularly and extracellularly. Consisting of 12 different isoforms, some of the proteins have been found to be released in the serum and to be correlated with various diseases including cancer. Differential expression of these proteins has been reported to result in cancer pathogenesis by modulating various cancer signaling pathways; hence, in this review, we present the recent studies that have investigated the roles of different kinds of FABPs in different types of cancer and any possible underlying mechanisms to better understand the role of FABPs in cancer progression.

AB - Fatty acid binding proteins (FABPs) are 15-kDa proteins responsible for the transport of fatty acids both intracellularly and extracellularly. Consisting of 12 different isoforms, some of the proteins have been found to be released in the serum and to be correlated with various diseases including cancer. Differential expression of these proteins has been reported to result in cancer pathogenesis by modulating various cancer signaling pathways; hence, in this review, we present the recent studies that have investigated the roles of different kinds of FABPs in different types of cancer and any possible underlying mechanisms to better understand the role of FABPs in cancer progression.

KW - Adipocytes

KW - Cancer

KW - Drug resistance

KW - FABPs

KW - Metastasis

UR - http://www.scopus.com/inward/record.url?scp=85060159830&partnerID=8YFLogxK

U2 - 10.14670/HH-18-014

DO - 10.14670/HH-18-014

M3 - Review article

C2 - 29911740

AN - SCOPUS:85060159830

SN - 0213-3911

VL - 34

SP - 1

EP - 12

JO - Histology and Histopathology

JF - Histology and Histopathology

IS - 1

ER -

Emerging role of fatty acid binding proteins in cancer pathogenesis

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

More information

Other files and links

Fingerprint

Cite this