Emergence of carbapenem-resistant serotype K1 hypervirulent Klebsiella pneumoniae strains in China

Rong Zhang, Dachuan Lin, Edward Wai Chi Chan, Danxia Gu, Gong Xiang Chen, Sheng Chen

Research output: Journal article publicationJournal articleAcademic researchpeer-review

107 Citations (Scopus)

Abstract

We report the emergence of five carbapenem-resistant K1 hypervirulent Klebsiella pneumoniae (hvKP) strains which caused fatal infections in hospital patients in Zhejiang Province, China, upon entry through surgical wounds. Genotyping results revealed the existence of three genetically related strains which exhibited a new sequence type, ST1797, and revealed that all strains harbored the magA and wcaG virulence genes and a plasmid-borne blaKPC-2gene. These findings indicate that K1 hvKP is simultaneously hypervirulent, multidrug resistant, and transmissible.
Original languageEnglish
Pages (from-to)709-711
Number of pages3
JournalAntimicrobial Agents and Chemotherapy
Volume60
Issue number1
DOIs
Publication statusPublished - 1 Jan 2016

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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