Ltd. Electrospun biodegradable micro-/nanopolyester fibers have attracted increasing interest for the designing of site-specific controlled drug delivery system in the body. Currently, different types of drugs, hydrophobic or hydrophilic drugs, growth factors, or genes have been entrapped within the interior or physically immobilized on the surfaces of these fibers by versatile drug encapsulation methods, including blending, coaxial process, emulsion, and surface modification. The advance in creating drug-loaded micro-/nanofibers have made them applicable in numerous clinical applications, including wound dressing, cancer therapy, adhesion barrier, as well as regeneration of human soft and hard tissues. This book chapter reviews micro-/nanofibers associated with different drugs and their clinical applications.
|Title of host publication
|Handbook of Polyester Drug Delivery Systems
|Pan Stanford Publishing Pte. Ltd.
|Number of pages
|Published - 9 Jun 2016
ASJC Scopus subject areas
- General Medicine
- Pharmacology, Toxicology and Pharmaceutics(all)
- General Engineering
- General Materials Science