Electrospun biodegradable polyester micro-/nanofibers for drug delivery and their clinical applications

Xin Zhao, Divia Hobson, Zhi Yuan William Lin, Wenguo Cuia

Research output: Chapter in book / Conference proceedingChapter in an edited book (as author)Academic researchpeer-review

Abstract

Ltd. Electrospun biodegradable micro-/nanopolyester fibers have attracted increasing interest for the designing of site-specific controlled drug delivery system in the body. Currently, different types of drugs, hydrophobic or hydrophilic drugs, growth factors, or genes have been entrapped within the interior or physically immobilized on the surfaces of these fibers by versatile drug encapsulation methods, including blending, coaxial process, emulsion, and surface modification. The advance in creating drug-loaded micro-/nanofibers have made them applicable in numerous clinical applications, including wound dressing, cancer therapy, adhesion barrier, as well as regeneration of human soft and hard tissues. This book chapter reviews micro-/nanofibers associated with different drugs and their clinical applications.
Original languageEnglish
Title of host publicationHandbook of Polyester Drug Delivery Systems
PublisherPan Stanford Publishing Pte. Ltd.
Pages125-158
Number of pages34
ISBN (Electronic)9789814669665
ISBN (Print)9789814669658
DOIs
Publication statusPublished - 9 Jun 2016
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)
  • Engineering(all)
  • Materials Science(all)

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