TY - JOUR
T1 - Electrospray ionization mass spectrometry with wooden tips: A review
AU - Hu, Bin
AU - Yao, Zhong Ping
N1 - Funding Information:
We would like to thank the National Natural Science Foundation of China (Grant Nos. 21804053 and 81874306 ), Research Grants Council (Grant Nos. 15304020 , 15304117 , R5013-19 , R4005-18 and C4002-17G ), the University Research Facility in Chemical and Environmental Analysis and the University Research Facility in Life Sciences of The Hong Kong Polytechnic University for their supports to this work.
Publisher Copyright:
© 2021 Elsevier B.V.
PY - 2022/5/29
Y1 - 2022/5/29
N2 - Electrospray ionization (ESI) is a powerful ionization technique in mass spectrometry (MS). There has been an increasing interest for the new development of ESI technique to extend its applications. ESI-MS with wooden tips (wooden-tip ESI-MS), an ESI technique invented in 2011, enabled not only new applications but also new insights into the ESI mechanism. In this review, the technical aspects of wooden-tip ESI-MS are described, the new features of wooden-tip ESI-MS for sampling and ionization of analytes are highlighted, and the important applications of wooden-tip ESI-MS in various fields in the past 10 years, including food safety, forensic investigation, environmental analysis, biomedical analysis and protein study, are summarized. The perspectives on the further development and applications of wooden-tip ESI-MS are also discussed.
AB - Electrospray ionization (ESI) is a powerful ionization technique in mass spectrometry (MS). There has been an increasing interest for the new development of ESI technique to extend its applications. ESI-MS with wooden tips (wooden-tip ESI-MS), an ESI technique invented in 2011, enabled not only new applications but also new insights into the ESI mechanism. In this review, the technical aspects of wooden-tip ESI-MS are described, the new features of wooden-tip ESI-MS for sampling and ionization of analytes are highlighted, and the important applications of wooden-tip ESI-MS in various fields in the past 10 years, including food safety, forensic investigation, environmental analysis, biomedical analysis and protein study, are summarized. The perspectives on the further development and applications of wooden-tip ESI-MS are also discussed.
KW - Direct analysis
KW - Electrospray ionization
KW - Ionization mechanism
KW - Mass spectrometry
KW - New features
KW - Wooden tips
UR - http://www.scopus.com/inward/record.url?scp=85116808043&partnerID=8YFLogxK
U2 - 10.1016/j.aca.2021.339136
DO - 10.1016/j.aca.2021.339136
M3 - Review article
C2 - 35569859
AN - SCOPUS:85116808043
SN - 0003-2670
VL - 1209
JO - Analytica Chimica Acta
JF - Analytica Chimica Acta
M1 - 339136
ER -