Efficient Selenium-Catalyzed Selective C(sp3)−H Oxidation of Benzylpyridines with Molecular Oxygen

Weiwei Jin; Poonnapa Zheng; Wing Tak Wong; Ga Lai Law

doi:10.1002/adsc.201601065

Efficient Selenium-Catalyzed Selective C(sp³)−H Oxidation of Benzylpyridines with Molecular Oxygen

Weiwei Jin
, Poonnapa Zheng
, Wing Tak Wong
, Ga Lai Law

Research output: Journal article publication › Journal article › Academic research › peer-review

57 Citations (Scopus)

Abstract

ï¿½ 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim An efficient selenium-catalyzed direct oxidation of benzylpyridines in aqueous DMSO has been successfully developed by using molecular oxygen as the oxidant. A variety of benzoylpyridines with broad functional group tolerance were obtained in modest to excellent yields and with exclusive chemoselectivity. (Figure presented.).

Original language	English
Pages (from-to)	1588-1593
Number of pages	6
Journal	Advanced Synthesis and Catalysis
Volume	359
Issue number	9
DOIs	https://doi.org/10.1002/adsc.201601065
Publication status	Published - 1 Jan 2017

Keywords

C−H oxidation
heterocycles
molecular oxygen
selenium catalysis

ASJC Scopus subject areas

Catalysis
Organic Chemistry

More information

10.1002/adsc.201601065

http://hdl.handle.net/10397/101596

Cite this

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title = "Efficient Selenium-Catalyzed Selective C(sp3)−H Oxidation of Benzylpyridines with Molecular Oxygen",

abstract = "{\"i}¿½ 2017 Wiley-VCH Verlag GmbH \& Co. KGaA, Weinheim An efficient selenium-catalyzed direct oxidation of benzylpyridines in aqueous DMSO has been successfully developed by using molecular oxygen as the oxidant. A variety of benzoylpyridines with broad functional group tolerance were obtained in modest to excellent yields and with exclusive chemoselectivity. (Figure presented.).",

keywords = "C−H oxidation, heterocycles, molecular oxygen, selenium catalysis",

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AU - Jin, Weiwei

AU - Zheng, Poonnapa

AU - Wong, Wing Tak

AU - Law, Ga Lai

PY - 2017/1/1

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AB - ï¿½ 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim An efficient selenium-catalyzed direct oxidation of benzylpyridines in aqueous DMSO has been successfully developed by using molecular oxygen as the oxidant. A variety of benzoylpyridines with broad functional group tolerance were obtained in modest to excellent yields and with exclusive chemoselectivity. (Figure presented.).

KW - C−H oxidation

KW - heterocycles

KW - molecular oxygen

KW - selenium catalysis

UR - https://www.scopus.com/pages/publications/85011982134

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DO - 10.1002/adsc.201601065

M3 - Journal article

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VL - 359

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JO - Advanced Synthesis and Catalysis

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