Efficient Selenium-Catalyzed Selective C(sp3)−H Oxidation of Benzylpyridines with Molecular Oxygen

Weiwei Jin, Poonnapa Zheng, Wing Tak Wong, Ga Lai Law

Research output: Journal article publicationJournal articleAcademic researchpeer-review

40 Citations (Scopus)

Abstract

� 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim An efficient selenium-catalyzed direct oxidation of benzylpyridines in aqueous DMSO has been successfully developed by using molecular oxygen as the oxidant. A variety of benzoylpyridines with broad functional group tolerance were obtained in modest to excellent yields and with exclusive chemoselectivity. (Figure presented.).
Original languageEnglish
Pages (from-to)1588-1593
Number of pages6
JournalAdvanced Synthesis and Catalysis
Volume359
Issue number9
DOIs
Publication statusPublished - 1 Jan 2017

Keywords

  • C−H oxidation
  • heterocycles
  • molecular oxygen
  • selenium catalysis

ASJC Scopus subject areas

  • Catalysis
  • Organic Chemistry

Cite this