Efficient assembly of multi-walled carbon nanotube-CdSe/ZnS quantum dot hybrids with high biocompatibility and fluorescence property

Yingying Zhang; Weiling Qin; Hao Tang; Feng Yan; Liang Tan; Qingji Xie; Ming Ma; Youyu Zhang; Shouzhuo Yao

doi:10.1016/j.colsurfb.2011.05.038

Efficient assembly of multi-walled carbon nanotube-CdSe/ZnS quantum dot hybrids with high biocompatibility and fluorescence property

Yingying Zhang, Weiling Qin, Hao Tang, Feng Yan, Liang Tan, Qingji Xie, Ming Ma, Youyu Zhang, Shouzhuo Yao

Research output: Journal article publication › Journal article › Academic research › peer-review

19 Citations (Scopus)

Abstract

CdSe/ZnS core-shell quantum dots (QDs) were efficiently tethered onto polyamidoamine dendrimer-modified multi-walled carbon nanotubes (MWCNTs) by covalent linkage and mercapto-mediated assembly. The obtained MWCNT-QD hybrids were both photophysically and morphologically characterized. The QDs are well-distributed on single nanotube surface in high density and the assembly of QDs onto MWCNTs does not change the fluorescence emission wavelength of QDs but significantly decreases the emission density. Cytotoxicity of MWCNT-QD hybrids to HeLa cells and their fluorescence property in living cell system were evaluated in detail. The hybrids show a little effect on cell viability even at very high concentration (100μgmL-1). Moreover, they possess intense red fluorescence signal under optical fluorescence microscopy and good fluorescence stability over 72-h exposure in living cell system.

Original language	English
Pages (from-to)	346-352
Number of pages	7
Journal	Colloids and Surfaces B: Biointerfaces
Volume	87
Issue number	2
DOIs	https://doi.org/10.1016/j.colsurfb.2011.05.038
Publication status	Published - 15 Oct 2011

Keywords

CdSe/ZnS quantum dots
Cytotoxicity
Fluorescence property in living cell system
Hybrids
Multi-walled carbon nanotubes

ASJC Scopus subject areas

Biotechnology
Surfaces and Interfaces
Physical and Theoretical Chemistry
Colloid and Surface Chemistry

More information

10.1016/j.colsurfb.2011.05.038

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title = "Efficient assembly of multi-walled carbon nanotube-CdSe/ZnS quantum dot hybrids with high biocompatibility and fluorescence property",

abstract = "CdSe/ZnS core-shell quantum dots (QDs) were efficiently tethered onto polyamidoamine dendrimer-modified multi-walled carbon nanotubes (MWCNTs) by covalent linkage and mercapto-mediated assembly. The obtained MWCNT-QD hybrids were both photophysically and morphologically characterized. The QDs are well-distributed on single nanotube surface in high density and the assembly of QDs onto MWCNTs does not change the fluorescence emission wavelength of QDs but significantly decreases the emission density. Cytotoxicity of MWCNT-QD hybrids to HeLa cells and their fluorescence property in living cell system were evaluated in detail. The hybrids show a little effect on cell viability even at very high concentration (100μgmL-1). Moreover, they possess intense red fluorescence signal under optical fluorescence microscopy and good fluorescence stability over 72-h exposure in living cell system.",

keywords = "CdSe/ZnS quantum dots, Cytotoxicity, Fluorescence property in living cell system, Hybrids, Multi-walled carbon nanotubes",

author = "Yingying Zhang and Weiling Qin and Hao Tang and Feng Yan and Liang Tan and Qingji Xie and Ming Ma and Youyu Zhang and Shouzhuo Yao",

year = "2011",

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AU - Zhang, Yingying

AU - Qin, Weiling

AU - Tang, Hao

AU - Yan, Feng

AU - Tan, Liang

AU - Xie, Qingji

AU - Ma, Ming

AU - Zhang, Youyu

AU - Yao, Shouzhuo

PY - 2011/10/15

Y1 - 2011/10/15

N2 - CdSe/ZnS core-shell quantum dots (QDs) were efficiently tethered onto polyamidoamine dendrimer-modified multi-walled carbon nanotubes (MWCNTs) by covalent linkage and mercapto-mediated assembly. The obtained MWCNT-QD hybrids were both photophysically and morphologically characterized. The QDs are well-distributed on single nanotube surface in high density and the assembly of QDs onto MWCNTs does not change the fluorescence emission wavelength of QDs but significantly decreases the emission density. Cytotoxicity of MWCNT-QD hybrids to HeLa cells and their fluorescence property in living cell system were evaluated in detail. The hybrids show a little effect on cell viability even at very high concentration (100μgmL-1). Moreover, they possess intense red fluorescence signal under optical fluorescence microscopy and good fluorescence stability over 72-h exposure in living cell system.

AB - CdSe/ZnS core-shell quantum dots (QDs) were efficiently tethered onto polyamidoamine dendrimer-modified multi-walled carbon nanotubes (MWCNTs) by covalent linkage and mercapto-mediated assembly. The obtained MWCNT-QD hybrids were both photophysically and morphologically characterized. The QDs are well-distributed on single nanotube surface in high density and the assembly of QDs onto MWCNTs does not change the fluorescence emission wavelength of QDs but significantly decreases the emission density. Cytotoxicity of MWCNT-QD hybrids to HeLa cells and their fluorescence property in living cell system were evaluated in detail. The hybrids show a little effect on cell viability even at very high concentration (100μgmL-1). Moreover, they possess intense red fluorescence signal under optical fluorescence microscopy and good fluorescence stability over 72-h exposure in living cell system.

KW - CdSe/ZnS quantum dots

KW - Cytotoxicity

KW - Fluorescence property in living cell system

KW - Hybrids

KW - Multi-walled carbon nanotubes

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SP - 346

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JO - Colloids and Surfaces B: Biointerfaces

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Efficient assembly of multi-walled carbon nanotube-CdSe/ZnS quantum dot hybrids with high biocompatibility and fluorescence property

Abstract

Keywords

ASJC Scopus subject areas

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