Efficient and selective singlet oxygen sensitized NIR luminescence of a neodymium(III) complex and its application in biological imaging

Wai Sum Lo; Hongguang Li; Ga Lai Law; Wing Tak Wong; Ka Leung Wong

doi:10.1016/j.jlumin.2014.12.051

Efficient and selective singlet oxygen sensitized NIR luminescence of a neodymium(III) complex and its application in biological imaging

Wai Sum Lo
, Hongguang Li
, Ga Lai Law
, Wing Tak Wong
, Ka Leung Wong

The Hong Kong Polytechnic University

Research output: Journal article publication › Journal article › Academic research › peer-review

22 Citations (Scopus)

Abstract

A responsive neodymium NIR emission (⁴F_3/2→⁴I_{11/2, 9/2}) was recorded upon binding with singlet oxygen (K_B=1.79×10⁶ M^-1) via the anthracene moiety. The motif ytterbium analog served as a negative control with no significant NIR enhancement/quenching with the addition of the same amount of singlet oxygen. Our complex was also found to react with ¹O₂ generated by a known photosensitizer TMPyP inside HeLa cells without inducing cell death and display no significant cytotoxicity.

Original language	English
Pages (from-to)	549-552
Number of pages	4
Journal	Journal of Luminescence
Volume	169
DOIs	https://doi.org/10.1016/j.jlumin.2014.12.051
Publication status	Published - 1 Jan 2016

Keywords

Lanthanide
Neodymium
NIR luminescence
Singlet oxygen probe

ASJC Scopus subject areas

Biophysics
General Chemistry
Atomic and Molecular Physics, and Optics
Biochemistry
Condensed Matter Physics

More information

10.1016/j.jlumin.2014.12.051

Cite this

@article{571c8911a68d4e378867e163ccb56346,

title = "Efficient and selective singlet oxygen sensitized NIR luminescence of a neodymium(III) complex and its application in biological imaging",

abstract = "A responsive neodymium NIR emission (4F3/2→4I11/2, 9/2) was recorded upon binding with singlet oxygen (KB=1.79{\texttimes}106 M-1) via the anthracene moiety. The motif ytterbium analog served as a negative control with no significant NIR enhancement/quenching with the addition of the same amount of singlet oxygen. Our complex was also found to react with 1O2 generated by a known photosensitizer TMPyP inside HeLa cells without inducing cell death and display no significant cytotoxicity.",

keywords = "Lanthanide, Neodymium, NIR luminescence, Singlet oxygen probe",

author = "Lo, \{Wai Sum\} and Hongguang Li and Law, \{Ga Lai\} and Wong, \{Wing Tak\} and Wong, \{Ka Leung\}",

note = "Publisher Copyright: {\textcopyright} 2014 Elsevier B.V.",

year = "2016",

month = jan,

day = "1",

doi = "10.1016/j.jlumin.2014.12.051",

language = "English",

volume = "169",

pages = "549--552",

journal = "Journal of Luminescence",

issn = "0022-2313",

publisher = "Elsevier B.V.",

}

TY - JOUR

T1 - Efficient and selective singlet oxygen sensitized NIR luminescence of a neodymium(III) complex and its application in biological imaging

AU - Lo, Wai Sum

AU - Li, Hongguang

AU - Law, Ga Lai

AU - Wong, Wing Tak

AU - Wong, Ka Leung

PY - 2016/1/1

Y1 - 2016/1/1

N2 - A responsive neodymium NIR emission (4F3/2→4I11/2, 9/2) was recorded upon binding with singlet oxygen (KB=1.79×106 M-1) via the anthracene moiety. The motif ytterbium analog served as a negative control with no significant NIR enhancement/quenching with the addition of the same amount of singlet oxygen. Our complex was also found to react with 1O2 generated by a known photosensitizer TMPyP inside HeLa cells without inducing cell death and display no significant cytotoxicity.

AB - A responsive neodymium NIR emission (4F3/2→4I11/2, 9/2) was recorded upon binding with singlet oxygen (KB=1.79×106 M-1) via the anthracene moiety. The motif ytterbium analog served as a negative control with no significant NIR enhancement/quenching with the addition of the same amount of singlet oxygen. Our complex was also found to react with 1O2 generated by a known photosensitizer TMPyP inside HeLa cells without inducing cell death and display no significant cytotoxicity.

KW - Lanthanide

KW - Neodymium

KW - NIR luminescence

KW - Singlet oxygen probe

UR - https://www.scopus.com/pages/publications/84949106356

U2 - 10.1016/j.jlumin.2014.12.051

DO - 10.1016/j.jlumin.2014.12.051

M3 - Journal article

SN - 0022-2313

VL - 169

SP - 549

EP - 552

JO - Journal of Luminescence

JF - Journal of Luminescence

ER -

Efficient and selective singlet oxygen sensitized NIR luminescence of a neodymium(III) complex and its application in biological imaging

Abstract

Keywords

ASJC Scopus subject areas

More information

Other files and links

Fingerprint

Cite this