Efficient and selective singlet oxygen sensitized NIR luminescence of a neodymium(III) complex and its application in biological imaging

Wai Sum Lo, Hongguang Li, Ga Lai Law, Wing Tak Wong, Ka Leung Wong

Research output: Journal article publicationJournal articleAcademic researchpeer-review

15 Citations (Scopus)

Abstract

A responsive neodymium NIR emission (4F3/2→4I11/2, 9/2) was recorded upon binding with singlet oxygen (KB=1.79×106M-1) via the anthracene moiety. The motif ytterbium analog served as a negative control with no significant NIR enhancement/quenching with the addition of the same amount of singlet oxygen. Our complex was also found to react with1O2generated by a known photosensitizer TMPyP inside HeLa cells without inducing cell death and display no significant cytotoxicity.
Original languageEnglish
Pages (from-to)549-552
Number of pages4
JournalJournal of Luminescence
Volume169
DOIs
Publication statusPublished - 1 Jan 2016

Keywords

  • Lanthanide
  • Neodymium
  • NIR luminescence
  • Singlet oxygen probe

ASJC Scopus subject areas

  • Biophysics
  • Chemistry(all)
  • Atomic and Molecular Physics, and Optics
  • Biochemistry
  • Condensed Matter Physics

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