TY - JOUR
T1 - Efficacy of Mobile Instant Messaging-Delivered Brief Motivational Interviewing for Parents to Promote Physical Activity in Pediatric Cancer Survivors
T2 - A Randomized Clinical Trial
AU - Cheung, Ankie Tan
AU - Li, William Ho Cheung
AU - Ho, Laurie Long Kwan
AU - Chan, Godfrey Chi Fung
AU - Lam, Huen Sum
AU - Chung, Joyce Oi Kwan
N1 - Publisher Copyright:
© 2022 BMJ Publishing Group. All rights reserved.
PY - 2022
Y1 - 2022
N2 - Importance: Physical activity has beneficial effects that mitigate cancer- and treatment-related late effects. However, children who survive cancer are often physically inactive. Brief motivational interviewing may be an effective approach for increasing children's physical activity levels. Objective: To examine the effects of mobile instant messaging-delivered brief motivational interviewing for parents in promoting regular physical activity in children who have survived cancer. Design, Setting, and Participants: An assessor-blinded randomized clinical trial was conducted at 2 Hong Kong pediatric oncology outpatient clinics from March 1, 2019, to January 29, 2021. A total of 161 children who had survived cancer, aged 9 to 16 years, and their parents were randomized (1:1) to an intervention or control group. Interventions: The intervention group received a 6-month mobile instant messaging-delivered brief motivational interviewing using a strategy menu. Parent-child dyads in both groups received a health advice session and were directed to a physical activity website at baseline. Main Outcomes and Measures: The primary outcome was the children's physical activity levels at 12-month follow-up, measured by the Chinese University of Hong Kong: Physical Activity Rating for Children and Youth (total sores: 0-10, higher scores indicate greater physical activity levels). Secondary outcomes were cancer-related fatigue levels, handgrip strength, peak expiratory flow rate, and quality of life. Intention-to-treat analysis was performed. Results: Of the 161 children included in the study, 93 were boys (57.8%), and the mean (SD) age was 12.4 (2.4) years. Generalized estimating equation analyses showed a significant improvement in outcomes in the intervention group compared with the control group: physical activity levels (group-by-time interaction, 6 months: β = 3.09; 95% CI, 2.65-3.53; P <.001; 12 months: β = 3.91; 95% CI, 3.45-4.36; P <.001), cancer-related fatigue (6 months: β = -5.69; 95% CI, -8.03 to -3.35; P <.001; 12 months: β = -9.16; 95% CI, -11.31 to -7.00; P <.001), left handgrip strength (6 months: β = 2.69; 95% CI, 0.96-4.43; P =.002; 12 months: β = 5.52; 95% CI, 3.70-7.33; P <.001), right handgrip strength (6 months: β = 2.75; 95% CI, 1.01-4.50; P =.002; 12 months: β = 5.45; 95% CI, 3.62-7.27; P <.001), peak expiratory flow rate (12 months: β = 28.51; 95% CI, 16.10-40.92; P <.001), and quality of life (6 months: β = 5.01; 95% CI, 1.19-8.82; P =.01); 12 months: β = 14.19; 95% CI, 10.84-17.54; P <.001). Conclusions and Relevance: In this randomized clinical trial, mobile instant messaging-delivered brief motivational interviewing was effective in promoting the adoption and maintenance of regular physical activity and ameliorating cancer- or treatment-related adverse effects in children who survived cancer.
AB - Importance: Physical activity has beneficial effects that mitigate cancer- and treatment-related late effects. However, children who survive cancer are often physically inactive. Brief motivational interviewing may be an effective approach for increasing children's physical activity levels. Objective: To examine the effects of mobile instant messaging-delivered brief motivational interviewing for parents in promoting regular physical activity in children who have survived cancer. Design, Setting, and Participants: An assessor-blinded randomized clinical trial was conducted at 2 Hong Kong pediatric oncology outpatient clinics from March 1, 2019, to January 29, 2021. A total of 161 children who had survived cancer, aged 9 to 16 years, and their parents were randomized (1:1) to an intervention or control group. Interventions: The intervention group received a 6-month mobile instant messaging-delivered brief motivational interviewing using a strategy menu. Parent-child dyads in both groups received a health advice session and were directed to a physical activity website at baseline. Main Outcomes and Measures: The primary outcome was the children's physical activity levels at 12-month follow-up, measured by the Chinese University of Hong Kong: Physical Activity Rating for Children and Youth (total sores: 0-10, higher scores indicate greater physical activity levels). Secondary outcomes were cancer-related fatigue levels, handgrip strength, peak expiratory flow rate, and quality of life. Intention-to-treat analysis was performed. Results: Of the 161 children included in the study, 93 were boys (57.8%), and the mean (SD) age was 12.4 (2.4) years. Generalized estimating equation analyses showed a significant improvement in outcomes in the intervention group compared with the control group: physical activity levels (group-by-time interaction, 6 months: β = 3.09; 95% CI, 2.65-3.53; P <.001; 12 months: β = 3.91; 95% CI, 3.45-4.36; P <.001), cancer-related fatigue (6 months: β = -5.69; 95% CI, -8.03 to -3.35; P <.001; 12 months: β = -9.16; 95% CI, -11.31 to -7.00; P <.001), left handgrip strength (6 months: β = 2.69; 95% CI, 0.96-4.43; P =.002; 12 months: β = 5.52; 95% CI, 3.70-7.33; P <.001), right handgrip strength (6 months: β = 2.75; 95% CI, 1.01-4.50; P =.002; 12 months: β = 5.45; 95% CI, 3.62-7.27; P <.001), peak expiratory flow rate (12 months: β = 28.51; 95% CI, 16.10-40.92; P <.001), and quality of life (6 months: β = 5.01; 95% CI, 1.19-8.82; P =.01); 12 months: β = 14.19; 95% CI, 10.84-17.54; P <.001). Conclusions and Relevance: In this randomized clinical trial, mobile instant messaging-delivered brief motivational interviewing was effective in promoting the adoption and maintenance of regular physical activity and ameliorating cancer- or treatment-related adverse effects in children who survived cancer.
UR - http://www.scopus.com/inward/record.url?scp=85132050217&partnerID=8YFLogxK
U2 - 10.1001/jamanetworkopen.2022.14600
DO - 10.1001/jamanetworkopen.2022.14600
M3 - Journal article
C2 - 35699959
AN - SCOPUS:85132050217
SP - E2214600
JO - JAMA network open
JF - JAMA network open
SN - 2574-3805
ER -