Effects of multiple washing on cotton fabrics containing berberine microcapsules with anti-Staphylococcus aureus activity

P. L. Lam, Li Li, C. W M Yuen, R. Gambari, R. S M Wong, C. H. Chui, K. H. Lam

Research output: Journal article publicationJournal articleAcademic researchpeer-review

12 Citations (Scopus)


The therapeutic efficiency and topical performance of drug-containing microcapsules varied when the drugs existed in an internal oil phase or an internal aqueous phase within the wall shell or wall matrix of microcapsules. In this study, chitosan-based (oil-in-water) and agar-gelatin-based (water-in-oil) microencapsulation systems containing berberine were applied to cotton fabrics to provide an anti-Staphylococcus aureus activity for textile materials. The berberine microcapsule-treated cotton samples were subjected to various washing cycles and their surface morphology, chemical compositions and antibacterial property were investigated after washing. The SEM images and Fourier transform infrared analysis showed that the amount of microcapsules on cotton samples decreased gradually with an increase in washing cycles. After 20 washing cycles, the cotton fabrics with agar-gelatin (water-in-oil) microcapsules containing berberine still exhibited the anti-S. aureus activity. However, the chitosan-based (oil-in-water) system did not show any growth inhibition towards S. aureus but only in the contact areas.
Original languageEnglish
Pages (from-to)143-150
Number of pages8
JournalJournal of Microencapsulation
Issue number2
Publication statusPublished - 1 Feb 2013


  • Chitosan
  • Controlled release
  • Gelatin
  • Microencapsulation

ASJC Scopus subject areas

  • Pharmaceutical Science
  • Colloid and Surface Chemistry
  • Physical and Theoretical Chemistry
  • Bioengineering
  • Organic Chemistry

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