Abstract
The objectives of this study is to assess the effect of prolonged loading on the skin blood flowmotion in rats as measured by Laser Doppler flowmetry (LDF) using wavelets transform and power spectral in the rat skin microcirculation. External pressure of 13.3kPa (100 mmHg) was applied to the trochanter area and the distal lateral tibia of Sprague-Dawley rats via two specifically designed pneumatic indentors. The loading duration was 6 hours/day for 4 consecutive days. The results showed that 1) spontaneous rhythmic activities were present in skin blood flow of anesthetized rats, 2) significant decrease of flowmotion power (p=0.023 for trochanter and p=0.043 for tibia) was found in the frequency range of 0.01-0.04Hz after prolonged loading. Our results suggested that reduced vasomotion in the frequency of 0.01-0.04 Hz might be involved in the mechanisms leading to pressure ulcer formation.
| Original language | English |
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| Title of host publication | Proceedings of the 2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005 |
| Pages | 597-600 |
| Number of pages | 4 |
| Volume | 7 VOLS |
| Publication status | Published - 1 Dec 2005 |
| Event | 2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005 - Shanghai, China Duration: 1 Sept 2005 → 4 Sept 2005 |
Conference
| Conference | 2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005 |
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| Country/Territory | China |
| City | Shanghai |
| Period | 1/09/05 → 4/09/05 |
Keywords
- Flowmotion/vasomotion
- Pressure ulcer
- Prolonged loading
- Skin microcirculation
- Wavelets transform
ASJC Scopus subject areas
- Signal Processing
- Biomedical Engineering
- Computer Vision and Pattern Recognition
- Health Informatics