TY - JOUR
T1 - Effect of Peritoneal Interposition Flap to Prevent Symptomatic Lymphoceles in Robot-Assisted Radical Prostatectomy with Pelvic Lymphadenectomy
T2 - A Meta-Analysis and Systematic Review
AU - Zhou, Junjie
AU - Zhou, Lin
AU - Duan, Xi
AU - Shuai, Hui
AU - Tan, Ying
AU - Xu, Qian
AU - Mao, Xiaorong
AU - Wang, Shanshan
AU - Wu, Tao
N1 - Funding Information:
This study was supported by City of Nanchong Strategic Cooperation with Local Universities Foundation of technology (Grant Nos. 20SXQT0305 and 18SXHZ0321), The Application and Basic Research Program of Sichuan Science and Technology Department (Grant No. 2022NSFSC0804), The Primary Health Development Research Center of Sichuan Province Program (Grant No. SWFZ21-C-98), The Medical Research project of Sichuan Medical Association (Grant No. S21061).
Publisher Copyright:
Copyright 2023, Mary Ann Liebert, Inc., publishers.
PY - 2023
Y1 - 2023
N2 - Background: This systematic review and meta-analysis investigated whether peritoneal interposition flap (PIF) prevent lymphocele formation after robot-assisted radical prostatectomy with extended pelvic lymph node dissection. Materials and Methods: We performed a systematic review and cumulative meta-analysis of the primary outcomes according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses, Assessing the Methodological Quality of Systematic Reviews guidelines and risk-of-bias tool. Five databases, including Medline, PubMed, Cochrane Library, Scopus, and Web of Science, were systematically searched. The time frame of the search was set from the creation of the database to February 2023. Results: Meta-analysis of symptomatic lymphoceles (sLCs) rates revealed significant difference between PIF and no PIF group (eight studies pooled; p = 0.005), The sLCs rates account for 2.6% (28/1074) and 7.1% (85/1186) in the PIF and no PIF group, respectively. The resulting odds ratio was 0.34 (95% confidence interval: 0.16-0.73), taking into account the heterogeneity of these studies (Q = 14.32, p = 0.05; I2 = 51%). Conclusion: PIF is an effective intraoperative modification on the prevention or reduction of sLC, which is worthy of further clinical promotion.
AB - Background: This systematic review and meta-analysis investigated whether peritoneal interposition flap (PIF) prevent lymphocele formation after robot-assisted radical prostatectomy with extended pelvic lymph node dissection. Materials and Methods: We performed a systematic review and cumulative meta-analysis of the primary outcomes according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses, Assessing the Methodological Quality of Systematic Reviews guidelines and risk-of-bias tool. Five databases, including Medline, PubMed, Cochrane Library, Scopus, and Web of Science, were systematically searched. The time frame of the search was set from the creation of the database to February 2023. Results: Meta-analysis of symptomatic lymphoceles (sLCs) rates revealed significant difference between PIF and no PIF group (eight studies pooled; p = 0.005), The sLCs rates account for 2.6% (28/1074) and 7.1% (85/1186) in the PIF and no PIF group, respectively. The resulting odds ratio was 0.34 (95% confidence interval: 0.16-0.73), taking into account the heterogeneity of these studies (Q = 14.32, p = 0.05; I2 = 51%). Conclusion: PIF is an effective intraoperative modification on the prevention or reduction of sLC, which is worthy of further clinical promotion.
KW - meta-analysis
KW - pelvic lymphadenectomy
KW - peritoneal interpolated flap
KW - peritoneal reapproximation
KW - peritoneal rotation flap
KW - systematic review
UR - http://www.scopus.com/inward/record.url?scp=85168718895&partnerID=8YFLogxK
U2 - 10.1089/end.2023.0127
DO - 10.1089/end.2023.0127
M3 - Review article
C2 - 37493580
AN - SCOPUS:85168718895
SN - 0892-7790
JO - Journal of Endourology
JF - Journal of Endourology
ER -