Effect of laser acupuncture therapy on bone and articular cartilage under simulated microgravity

Q. Wang; Xia Guo; X. Y. Wang; M. Q. Liu; Ming Zhang; Yongping Zheng; Hau Chung Man

doi:10.1007/978-3-642-14515-5_217

Effect of laser acupuncture therapy on bone and articular cartilage under simulated microgravity

Q. Wang, Xia Guo, X. Y. Wang, M. Q. Liu, Ming Zhang, Yongping Zheng, Hau Chung Man

Research output: Chapter in book / Conference proceeding › Conference article published in proceeding or book › Academic research › peer-review

1 Citation (Scopus)

Abstract

The objectives of this study are to investigate the changes in bone and articular cartilage in rat femur under 4-week tail suspension and to evaluate the therapeutic effects of laser acupuncture (LA). 18 rats were assigned into three groups. Group control (C) was under normal earth gravity, group tail-suspension (T) underwent tail suspension (TS) for 4 weeks, and group laser-acupuncture-therapy (L) were treated using LA at Yongquan (KI-1) and Housanli (ST-36) acupoint on left hindlimb during TS. Bone mineral density (BMD) was quantified by peripheral computed tomography (pQCT) and the thickness of articular cartilage was measured by high-resolution ultrasound biomicroscopy (UBM) before and after TS. It was found that TS resulted in a significant decrease in BMD of femoral distal metaphysis (p < 0.01) and femoral shaft (p < 0.05) and significant cartilage thinning at medial femoral condyle and patella (p < 0.05). With LA therapy, an increase was found in BMD and cartilage thickness. The histological stains show an evidence of the changes including trabecular rarefaction, and cartilage thinning, proteoglycan loss and cell clustering in articular cartilage in group T as well as the corresponding therapeutic effects of LA in group L. This study demonstrates that the 4-week simulated microgravity has negative effects on bone and articular cartilage while LA has therapeutic improvement on the quality of the tissues.

Original language	English
Title of host publication	6th World Congress of Biomechanics, WCB 2010 - In Conjunction with 14th International Conference on Biomedical Engineering, ICBME and 5th Asia Pacific Conference on Biomechanics, APBiomech
Pages	852-855
Number of pages	4
Volume	31 IFMBE
DOIs	https://doi.org/10.1007/978-3-642-14515-5_217
Publication status	Published - 22 Oct 2010
Event	6th World Congress of Biomechanics, WCB 2010 - In Conjunction with 14th International Conference on Biomedical Engineering, ICBME and 5th Asia Pacific Conference on Biomechanics, APBiomech - Singapore, Singapore Duration: 1 Aug 2010 → 6 Aug 2010

Conference

Conference	6th World Congress of Biomechanics, WCB 2010 - In Conjunction with 14th International Conference on Biomedical Engineering, ICBME and 5th Asia Pacific Conference on Biomechanics, APBiomech
Country/Territory	Singapore
City	Singapore
Period	1/08/10 → 6/08/10

Keywords

Articular cartilage
Bone
Laser acupuncture
Simulated microgravity

ASJC Scopus subject areas

Biomedical Engineering
Bioengineering

More information

10.1007/978-3-642-14515-5_217

Cite this

Wang, Q., Guo, X., Wang, X. Y., Liu, M. Q., Zhang, M., Zheng, Y., & Man, H. C. (2010). Effect of laser acupuncture therapy on bone and articular cartilage under simulated microgravity. In 6th World Congress of Biomechanics, WCB 2010 - In Conjunction with 14th International Conference on Biomedical Engineering, ICBME and 5th Asia Pacific Conference on Biomechanics, APBiomech (Vol. 31 IFMBE, pp. 852-855) https://doi.org/10.1007/978-3-642-14515-5_217

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title = "Effect of laser acupuncture therapy on bone and articular cartilage under simulated microgravity",

abstract = "The objectives of this study are to investigate the changes in bone and articular cartilage in rat femur under 4-week tail suspension and to evaluate the therapeutic effects of laser acupuncture (LA). 18 rats were assigned into three groups. Group control (C) was under normal earth gravity, group tail-suspension (T) underwent tail suspension (TS) for 4 weeks, and group laser-acupuncture-therapy (L) were treated using LA at Yongquan (KI-1) and Housanli (ST-36) acupoint on left hindlimb during TS. Bone mineral density (BMD) was quantified by peripheral computed tomography (pQCT) and the thickness of articular cartilage was measured by high-resolution ultrasound biomicroscopy (UBM) before and after TS. It was found that TS resulted in a significant decrease in BMD of femoral distal metaphysis (p < 0.01) and femoral shaft (p < 0.05) and significant cartilage thinning at medial femoral condyle and patella (p < 0.05). With LA therapy, an increase was found in BMD and cartilage thickness. The histological stains show an evidence of the changes including trabecular rarefaction, and cartilage thinning, proteoglycan loss and cell clustering in articular cartilage in group T as well as the corresponding therapeutic effects of LA in group L. This study demonstrates that the 4-week simulated microgravity has negative effects on bone and articular cartilage while LA has therapeutic improvement on the quality of the tissues.",

keywords = "Articular cartilage, Bone, Laser acupuncture, Simulated microgravity",

author = "Q. Wang and Xia Guo and Wang, {X. Y.} and Liu, {M. Q.} and Ming Zhang and Yongping Zheng and Man, {Hau Chung}",

year = "2010",

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doi = "10.1007/978-3-642-14515-5_217",

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booktitle = "6th World Congress of Biomechanics, WCB 2010 - In Conjunction with 14th International Conference on Biomedical Engineering, ICBME and 5th Asia Pacific Conference on Biomechanics, APBiomech",

note = "6th World Congress of Biomechanics, WCB 2010 - In Conjunction with 14th International Conference on Biomedical Engineering, ICBME and 5th Asia Pacific Conference on Biomechanics, APBiomech ; Conference date: 01-08-2010 Through 06-08-2010",

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Wang, Q, Guo, X, Wang, XY, Liu, MQ, Zhang, M , Zheng, Y & Man, HC 2010, Effect of laser acupuncture therapy on bone and articular cartilage under simulated microgravity. in 6th World Congress of Biomechanics, WCB 2010 - In Conjunction with 14th International Conference on Biomedical Engineering, ICBME and 5th Asia Pacific Conference on Biomechanics, APBiomech. vol. 31 IFMBE, pp. 852-855, 6th World Congress of Biomechanics, WCB 2010 - In Conjunction with 14th International Conference on Biomedical Engineering, ICBME and 5th Asia Pacific Conference on Biomechanics, APBiomech, Singapore, Singapore, 1/08/10. https://doi.org/10.1007/978-3-642-14515-5_217

Effect of laser acupuncture therapy on bone and articular cartilage under simulated microgravity. / Wang, Q.; Guo, Xia; Wang, X. Y. et al.
6th World Congress of Biomechanics, WCB 2010 - In Conjunction with 14th International Conference on Biomedical Engineering, ICBME and 5th Asia Pacific Conference on Biomechanics, APBiomech. Vol. 31 IFMBE 2010. p. 852-855.

Research output: Chapter in book / Conference proceeding › Conference article published in proceeding or book › Academic research › peer-review

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T1 - Effect of laser acupuncture therapy on bone and articular cartilage under simulated microgravity

AU - Wang, Q.

AU - Guo, Xia

AU - Wang, X. Y.

AU - Liu, M. Q.

AU - Zhang, Ming

AU - Zheng, Yongping

AU - Man, Hau Chung

PY - 2010/10/22

Y1 - 2010/10/22

N2 - The objectives of this study are to investigate the changes in bone and articular cartilage in rat femur under 4-week tail suspension and to evaluate the therapeutic effects of laser acupuncture (LA). 18 rats were assigned into three groups. Group control (C) was under normal earth gravity, group tail-suspension (T) underwent tail suspension (TS) for 4 weeks, and group laser-acupuncture-therapy (L) were treated using LA at Yongquan (KI-1) and Housanli (ST-36) acupoint on left hindlimb during TS. Bone mineral density (BMD) was quantified by peripheral computed tomography (pQCT) and the thickness of articular cartilage was measured by high-resolution ultrasound biomicroscopy (UBM) before and after TS. It was found that TS resulted in a significant decrease in BMD of femoral distal metaphysis (p < 0.01) and femoral shaft (p < 0.05) and significant cartilage thinning at medial femoral condyle and patella (p < 0.05). With LA therapy, an increase was found in BMD and cartilage thickness. The histological stains show an evidence of the changes including trabecular rarefaction, and cartilage thinning, proteoglycan loss and cell clustering in articular cartilage in group T as well as the corresponding therapeutic effects of LA in group L. This study demonstrates that the 4-week simulated microgravity has negative effects on bone and articular cartilage while LA has therapeutic improvement on the quality of the tissues.

AB - The objectives of this study are to investigate the changes in bone and articular cartilage in rat femur under 4-week tail suspension and to evaluate the therapeutic effects of laser acupuncture (LA). 18 rats were assigned into three groups. Group control (C) was under normal earth gravity, group tail-suspension (T) underwent tail suspension (TS) for 4 weeks, and group laser-acupuncture-therapy (L) were treated using LA at Yongquan (KI-1) and Housanli (ST-36) acupoint on left hindlimb during TS. Bone mineral density (BMD) was quantified by peripheral computed tomography (pQCT) and the thickness of articular cartilage was measured by high-resolution ultrasound biomicroscopy (UBM) before and after TS. It was found that TS resulted in a significant decrease in BMD of femoral distal metaphysis (p < 0.01) and femoral shaft (p < 0.05) and significant cartilage thinning at medial femoral condyle and patella (p < 0.05). With LA therapy, an increase was found in BMD and cartilage thickness. The histological stains show an evidence of the changes including trabecular rarefaction, and cartilage thinning, proteoglycan loss and cell clustering in articular cartilage in group T as well as the corresponding therapeutic effects of LA in group L. This study demonstrates that the 4-week simulated microgravity has negative effects on bone and articular cartilage while LA has therapeutic improvement on the quality of the tissues.

KW - Articular cartilage

KW - Bone

KW - Laser acupuncture

KW - Simulated microgravity

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DO - 10.1007/978-3-642-14515-5_217

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VL - 31 IFMBE

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T2 - 6th World Congress of Biomechanics, WCB 2010 - In Conjunction with 14th International Conference on Biomedical Engineering, ICBME and 5th Asia Pacific Conference on Biomechanics, APBiomech

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Wang Q, Guo X, Wang XY, Liu MQ, Zhang M , Zheng Y et al. Effect of laser acupuncture therapy on bone and articular cartilage under simulated microgravity. In 6th World Congress of Biomechanics, WCB 2010 - In Conjunction with 14th International Conference on Biomedical Engineering, ICBME and 5th Asia Pacific Conference on Biomechanics, APBiomech. Vol. 31 IFMBE. 2010. p. 852-855 doi: 10.1007/978-3-642-14515-5_217

Effect of laser acupuncture therapy on bone and articular cartilage under simulated microgravity

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