Effect of corneal incision features on anterior and posterior corneal astigmatism and higher-order aberrations after cataract surgery

Qin He, Jiani Huang, Xiaoying He, Wangshu Yu, Maurice Yap, Wei Han

Research output: Journal article publicationJournal articleAcademic researchpeer-review


Purpose: To evaluate the influence of 2.2 mm clear corneal incision (CCI) features in surgically induced astigmatism (SIA) and higher-order aberrations (HOAs) after cataract surgery. Methods: Right eyes of 92 subjects receiving 2.2 mm incision cataract surgery were involved. A total of 38 eyes were categorized as the intact incision group, and 54 eyes were the defective incision group. Pre- and postoperative (1 month and 6 months) corneal astigmatism and HOAs on anterior and posterior corneal surfaces, corneal volume, and corneal thickness (CT) were measured using Pentacam. The CCI features including incision length (IL), incision angles, distance from incision to central cornea (Dis-En/Ex), and CT at incision site were quantified using AS-OCT. Results: The defective incision group showed shorter IL and larger incision angles [false discovery rate (FDR) – p < 0.05]. Changes in CT at incision site were more pronounced for the defective incision group (FDR – p < 0.05). Some SIA parameters were related to the certain specific CCI features, especially IL (FDR – p < 0.05). Both groups exhibited significant increased 6 mm posterior corneal tHOAs at 1 month (Bonferroni corrected – p < 0.01) and the defective incision group showed increased 6 mm posterior tHOAs at 6 months (Bonferroni corrected – p = 0.023). There were characteristic correlations between Zernike terms and CCI features including IL, CT, Dis-En/Ex, and incision angles at 1 month, especially over 6 mm zone. Conclusion: The CCI deformities can affect corneal recovery and induce more HOAs at 1 month postoperatively. Such effects became minor, but could persist until 6 months. The IL combined with Angle-En/Ex was important factor influencing CCI integrity and corneal optical quality.

Original languageEnglish
JournalActa Ophthalmologica
Publication statusE-pub ahead of print - 4 Mar 2021


  • cataract surgery
  • clear corneal incision
  • higher-order aberrations
  • optical coherence tomography
  • surgically induced astigmatism

ASJC Scopus subject areas

  • Ophthalmology

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