Effect of bak foong pills on enhancing dopamine release from the amygdala of female rats.

Bin LIU; Xiaoli Dong; Junxia XIE; Yulin GOU; Dewi Kenneth ROWLANDS; Hsiao Chang CHAN

doi:10.1248/bpb.26.1028

Effect of bak foong pills on enhancing dopamine release from the amygdala of female rats.

Bin LIU, Xiaoli Dong, Junxia XIE, Yulin GOU, Dewi Kenneth ROWLANDS, Hsiao Chang CHAN

Research output: Journal article publication › Journal article › Academic research › peer-review

6 Citations (Scopus)

Abstract

To investigate whether Bak Foong Pills (BFP), a well-known gynaecological tonic, has a direct effect on the central nervous system, we employed the in vivo electrochemical detection technique, fast cyclic voltammetry (FCV), to measure the dopamine release from the mesolimbic structure-amygdala of both male and female rats. The results showed that intracerebroventricular BFP (0.75, 1.5 microg) treatment promoted dopamine release from the amygdala in both female and ovariectomized female rats. The BFP-induced response appeared within 5 min after addition of BFP and lasted for at least 40 min. However, no effect of BFP was observed in male rats for an observed period of up to 60 min. The results suggest that BFP may have gender-specific beneficial effect on dopaminergic functions of the amygdala.

Original language	English
Article number	PMID: 12843633
Pages (from-to)	1028-1030
Journal	Biological and Pharmaceutical Bulletin
Volume	26
Issue number	7
DOIs	https://doi.org/10.1248/bpb.26.1028
Publication status	Published - Jul 2003
Externally published	Yes

ASJC Scopus subject areas

Complementary and alternative medicine

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1248/bpb.26.1028

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title = "Effect of bak foong pills on enhancing dopamine release from the amygdala of female rats.",

abstract = "To investigate whether Bak Foong Pills (BFP), a well-known gynaecological tonic, has a direct effect on the central nervous system, we employed the in vivo electrochemical detection technique, fast cyclic voltammetry (FCV), to measure the dopamine release from the mesolimbic structure-amygdala of both male and female rats. The results showed that intracerebroventricular BFP (0.75, 1.5 microg) treatment promoted dopamine release from the amygdala in both female and ovariectomized female rats. The BFP-induced response appeared within 5 min after addition of BFP and lasted for at least 40 min. However, no effect of BFP was observed in male rats for an observed period of up to 60 min. The results suggest that BFP may have gender-specific beneficial effect on dopaminergic functions of the amygdala.",

author = "Bin LIU and Xiaoli Dong and Junxia XIE and Yulin GOU and ROWLANDS, {Dewi Kenneth} and CHAN, {Hsiao Chang}",

year = "2003",

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doi = "10.1248/bpb.26.1028",

language = "English",

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pages = "1028--1030",

journal = "Biological and Pharmaceutical Bulletin",

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}

TY - JOUR

T1 - Effect of bak foong pills on enhancing dopamine release from the amygdala of female rats.

AU - LIU, Bin

AU - Dong, Xiaoli

AU - XIE, Junxia

AU - GOU, Yulin

AU - ROWLANDS, Dewi Kenneth

AU - CHAN, Hsiao Chang

PY - 2003/7

Y1 - 2003/7

N2 - To investigate whether Bak Foong Pills (BFP), a well-known gynaecological tonic, has a direct effect on the central nervous system, we employed the in vivo electrochemical detection technique, fast cyclic voltammetry (FCV), to measure the dopamine release from the mesolimbic structure-amygdala of both male and female rats. The results showed that intracerebroventricular BFP (0.75, 1.5 microg) treatment promoted dopamine release from the amygdala in both female and ovariectomized female rats. The BFP-induced response appeared within 5 min after addition of BFP and lasted for at least 40 min. However, no effect of BFP was observed in male rats for an observed period of up to 60 min. The results suggest that BFP may have gender-specific beneficial effect on dopaminergic functions of the amygdala.

AB - To investigate whether Bak Foong Pills (BFP), a well-known gynaecological tonic, has a direct effect on the central nervous system, we employed the in vivo electrochemical detection technique, fast cyclic voltammetry (FCV), to measure the dopamine release from the mesolimbic structure-amygdala of both male and female rats. The results showed that intracerebroventricular BFP (0.75, 1.5 microg) treatment promoted dopamine release from the amygdala in both female and ovariectomized female rats. The BFP-induced response appeared within 5 min after addition of BFP and lasted for at least 40 min. However, no effect of BFP was observed in male rats for an observed period of up to 60 min. The results suggest that BFP may have gender-specific beneficial effect on dopaminergic functions of the amygdala.

U2 - 10.1248/bpb.26.1028

DO - 10.1248/bpb.26.1028

M3 - Journal article

SN - 0918-6158

VL - 26

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EP - 1030

JO - Biological and Pharmaceutical Bulletin

JF - Biological and Pharmaceutical Bulletin

IS - 7

M1 - PMID: 12843633

ER -

Effect of bak foong pills on enhancing dopamine release from the amygdala of female rats.

Abstract

ASJC Scopus subject areas

UN SDGs

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