Do fenestrations affect the performance of orthokeratology lenses?

Purpose.: To investigate the effect of lens fenestrations on the performance of orthokeratology lenses. Methods.: Twenty-two subjects (aged 11 to 31 years) were fitted with identical reverse geometry orthokeratology lenses in the two eyes. One eye was randomly designated to wear a lens with three 0.20 mm fenestrations at 120° intervals placed at the junction of the reverse and alignment curves. The lens for the other eye was not fenestrated. Subjects were reviewed at 1 week, 1 month, 3 months, 6 months, and 1 year after fitting. Data were collected on refraction, visual performance, incidences and severity of corneal staining, lens binding, and corneal pigmented arc. Results.: Fifteen subjects achieved full correction in OU. There were no statistically significant differences in refractive and corneal changes, visual performance, incidences and severity of corneal staining and corneal pigmented arc formation between the two eyes. The incidence of lens binding was consistently higher in eyes wearing non-fenestrated lenses but was not statistically significant. Severity of lens binding, however, was statistically significant at the 1-, 3-, 6- and 12-month visits, with the non-fenestrated lenses causing more severe binding. Conclusions.: The addition of fenestrations to orthokeratology lenses has no effect on the efficacy of the treatment or outcomes in low to moderate myopic subjects. However, the severity of lens binding is reduced. Fenestrating reverse geometry lenses may be of assistance in cases where lens binding is a problem.