Distribution of nitric oxide syntheses in the retinas of WISTAR and RCS rats

Feng Pan, Wei WANG (Corresponding Author), Huirong Zhang, Debo You, Lei Ren, Li Shen

Research output: Journal article publicationJournal articleAcademic researchpeer-review


Objective: To determine the difference in localization of Nitric Oxide Syntheses (NOS) in the retinas of Wistar rats and Royal College of Surgeons (RCS) rats. Methods: Immunocytochemistry staining technique was used and observed under light microscopy. Six eyes of 74d's Wistar rats and RCS rats were divided and processed for light microscopic analysis. The quantity of NOS-positive amacrine cells was gauged. Results: The NOS-positive amacrine cells could he observed in inner plexiform layer(IPL) of the equation, ore serratas and posterior pole. There were significant differences in the numbers of the NOS-positive amacrine cells between the RCS rats and the Wistar rats. Conclusion: Due to photoreceptor cell degeneration, the quantity of the NOS-positive amacrine cells in the RCS rats' retina is less than that in the Wistar rats'.
Original languageChinese (Simplified)
Pages (from-to)412-414
Number of pages3
JournalChinese Ophthalmic Research
Issue number5
Publication statusPublished - Oct 2000
Externally publishedYes


  • Nitric oxide
  • Nitric oxide syntheses

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

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