Dioxiranes generated in situ from pyruvates and oxone as environmentally friendly oxidizing agents for disinfection

Man Kin Wong, Tak Chung Chan, Wai Yee Chan, Wing Kei Chan, Lilian L.P. Vrijmoed, Desmond K. O'Toole, Chi Ming Che

Research output: Journal article publicationJournal articleAcademic researchpeer-review

11 Citations (Scopus)


Dioxiranes generated in situ from pyruvates (α-keto esters) and Oxone have been found to be environmentally friendly oxidizing agents for disinfection. These oxidizing agents were highly effective for destruction of various strains of bacteria, fungi, and bacterial endospores in a wide temperature range with exceptional stability. Notably, by using an aqueous solution of methyl pyruvate (1a) and Oxone/NaHCO3, complete destruction of bacteria such as Staphylococcus aureusand fungus Penicillium corylophilum was achieved within 5 min at 20 °C at neutral pH. Highly chemical-resistant bacterial endospores of Bacillus cereus could also be destroyed. The high antibacterial activity of 1a could be attributed to its strong electron-withdrawing α-ester group.
Original languageEnglish
Pages (from-to)625-630
Number of pages6
JournalEnvironmental Science and Technology
Issue number2
Publication statusPublished - 15 Jan 2006
Externally publishedYes

ASJC Scopus subject areas

  • Chemistry(all)
  • Environmental Chemistry

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