Diode laser hair removal does not interfere with botulinum toxin a treatment against axillary hyperhidrosis

A. Paul, G. Kranz, A. Schindl, Georg Kranz, E. Auff, T. Sycha

Research output: Journal article publicationJournal articleAcademic researchpeer-review

7 Citations (Scopus)


Background and Objective: The possible interference of combined laser hair removal and Botulinum toxin A (BoNT/A) injections in the treatment of axillary hyperhidrosis has not previously been explored. In order to examine this potential interference, we assessed the effect of BoNT/A on axillary hyperhidrosis with and without concomitant diode laser axillary hair removal. Study Design/Materials and Methods: In a prospective, double blind, randomized cross over trial, nine patients suffering from primary axillary hyperhidrosis were laser-treated on one randomly assigned axilla. One week later, both axillas were injected intradermally with BoNT/A (100 MU per axilla). During the same session, the previously untreated axilla was lasered. Axillary sweat rates (in g/5 minutes.) were determined by gravimetry and compared at rest, during mental exercise, and during physical exercise. Additionally, subjective outcome measures were assessed by a visual analogue scale, Dermatology Life Quality Index, and Global Clinical Impression score. Results: No differences were found regarding the effect of BoNT/A on previously laser-treated and laser co-treated sides over time course for any of the outcome parameters. Sweat production was reduced 3 weeks after BoNT/A treatment by 93.5% at rest, 96.5% during mental exercise, and 67% during physical exercise. Conclusions: Concomitant laser hair removal does not interfere with BoNT/A treatment on axillary hyperhidrosis. © 2010 Wiley-Liss, Inc.
Original languageEnglish
Pages (from-to)211-214
Number of pages4
JournalLasers in Surgery and Medicine
Issue number3
Publication statusPublished - 1 Mar 2010
Externally publishedYes


  • Axillary hyperhidrosis
  • Botulinum toxin A
  • Diode laser hair removal
  • Interference

ASJC Scopus subject areas

  • Surgery
  • Dermatology

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