@inproceedings{3ecdd2ecae8d43bfb9420ef835192c9f,
title = "Diagnosis-on-a-chip: A microfluidic platform for cell culture and virus assays",
abstract = "A high-throughput microfluidic chip for cell culture and immunofluorescence virus assays is presented in this paper. The chip is fabricated by laser engraving technology with the polymer material polymethylmethacrylate (PMMA). Madin-Darby canine kidney (MDCK) cell line has been successfully loaded, cultured and passaged in culturing chambers with 1mm diameter and 1.5 µl volume; and rapid growth of influenza A virus (H3N2) in MDCK cells cultured has been observed and proved by immunoflorescence assay. This kind of cell culture array could offer a platform for virus growth testing for vaccine production and also is promising for early diagnosis and drug screening. in drug screening, bioinformatics, and quantitative cell biology.",
keywords = "In situ observation, Influenza A, Lab on a chip, MDCK cells",
author = "Xuming Zhang and R. Chua and Yap, {P. H.} and Liu, {A. Q.}",
note = "Publisher Copyright: {\textcopyright} 2007 CBMS.; 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007 ; Conference date: 07-10-2007 Through 11-10-2007",
year = "2007",
language = "English",
series = "Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007",
publisher = "Chemical and Biological Microsystems Society",
pages = "694--696",
editor = "Jean-Louis Viovy and Patrick Tabeling and Stephanie Descroix and Laurent Malaquin",
booktitle = "Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007",
}
