TY - JOUR
T1 - Diabetes mellitus and its association with central obesity and disability among older adults
T2 - A global perspective
AU - Tyrovolas, Stefanos
AU - Koyanagi, Ai
AU - Garin, Noe
AU - Olaya, Beatriz
AU - Ayuso-Mateos, Jose Luis
AU - Miret, Marta
AU - Chatterji, Somnath
AU - Tobiasz-Adamczyk, Beata
AU - Koskinen, Seppo
AU - Leonardi, Matilde
AU - Haro, Josep Maria
N1 - Publisher Copyright:
© 2015 Elsevier Inc.
PY - 2015/4/1
Y1 - 2015/4/1
N2 - The aim of the study was to evaluate the association between various factors and diabetes type II (DM) with a particular emphasis on indicators of central obesity, and to compare the effect of DM on disability among elder populations (≥. 50. years old) in nine countries. Data were available for 52,946 people aged ≥. 18. years who participated in the WHO Study on global AGEing and adult health and the Collaborative Research on Ageing in Europe studies conducted between 2007 and 2012. DM was defined as self-report of physician diagnosis. Height, weight, and waist circumference were measured. Disability status was assessed with the WHODAS II questionnaire. The overall prevalence of DM was 7.9% and ranged from 3.8% (Ghana) to 17.6% (Mexico). A 10. cm increase in waist circumference and waist-to-height ratio of >. 0.5 were associated with a significant 1.26 (India) to 1.77 (Finland), and 1.68 (China, Spain) to 5.40 (Finland) times higher odds for DM respectively. No significant associations were observed in Mexico and South Africa. DM was associated with significantly higher disability status in all countries except Mexico in the model adjusted for demographics and smoking. The inclusion of chronic conditions associated with diabetes in the model attenuated the coefficients in varying degrees depending on the country. A considerable proportion of the studied older population had DM. Central obesity may be a key factor for the prevention of DM among older populations globally. Prevention of DM especially among the older population globally may contribute to reducing the burden of disability.
AB - The aim of the study was to evaluate the association between various factors and diabetes type II (DM) with a particular emphasis on indicators of central obesity, and to compare the effect of DM on disability among elder populations (≥. 50. years old) in nine countries. Data were available for 52,946 people aged ≥. 18. years who participated in the WHO Study on global AGEing and adult health and the Collaborative Research on Ageing in Europe studies conducted between 2007 and 2012. DM was defined as self-report of physician diagnosis. Height, weight, and waist circumference were measured. Disability status was assessed with the WHODAS II questionnaire. The overall prevalence of DM was 7.9% and ranged from 3.8% (Ghana) to 17.6% (Mexico). A 10. cm increase in waist circumference and waist-to-height ratio of >. 0.5 were associated with a significant 1.26 (India) to 1.77 (Finland), and 1.68 (China, Spain) to 5.40 (Finland) times higher odds for DM respectively. No significant associations were observed in Mexico and South Africa. DM was associated with significantly higher disability status in all countries except Mexico in the model adjusted for demographics and smoking. The inclusion of chronic conditions associated with diabetes in the model attenuated the coefficients in varying degrees depending on the country. A considerable proportion of the studied older population had DM. Central obesity may be a key factor for the prevention of DM among older populations globally. Prevention of DM especially among the older population globally may contribute to reducing the burden of disability.
KW - Diabetes mellitus
KW - Disability
KW - Obesity
KW - Older adults
KW - Waist circumference
KW - Waist-to-height ratio
UR - http://www.scopus.com/inward/record.url?scp=84923233683&partnerID=8YFLogxK
U2 - 10.1016/j.exger.2015.02.010
DO - 10.1016/j.exger.2015.02.010
M3 - Journal article
C2 - 25688991
AN - SCOPUS:84923233683
SN - 0531-5565
VL - 64
SP - 70
EP - 77
JO - Experimental Gerontology
JF - Experimental Gerontology
ER -