Development of medically hygienic socks loaded with antifungal microcapsules for patients with athlete's foot

Li Wei Liu, Yiu Wan Yip, Chun Wah Marcus Yuen, Hing Cheong Cheung, Chi Wai Kan

Research output: Chapter in book / Conference proceedingConference article published in proceeding or bookAcademic researchpeer-review

Abstract

Nowadays, healthcare and hygiene products are becoming more and more important in the field of technical textiles because of the specificity of their end uses. In this study, we have developed a pair of hygienic socks loaded with antifungal microcapsules especially for the treatment of athlete's foot (tinea pedis). First, antifungal clotrimazole/chitosan microcapsules are prepared via an oil-in-water emulsion technique and socks with moisture control are studied and selected. Then, medical hygienic socks with drug loaded microcapsules are developed by spraying the clotrimazole/chitosan microcapsules onto the socks. The socks have been studied in a preliminary clinical study. The complete cure rate of tinea pedis is significantly better in the active group in comparison with the control group (84.62% vs. 42.85%, p = 0.011) at the end of a 4-week period.
Original languageEnglish
Title of host publicationTextile Bioengineering and Informatics Symposium Proceedings 2014 - 7th Textile Bioengineering and Informatics Symposium, TBIS 2014, in conjunction with the 5th Asian Protective Clothing Conference, APCC 2014
PublisherBinary Information Press
Pages184-190
Number of pages7
Publication statusPublished - 1 Jan 2014
Event7th Textile Bioengineering and Informatics Symposium, TBIS 2014, in conjunction with the 5th Asian Protective Clothing Conference, APCC 2014 - The Hong Kong Polytechnic University, Hong Kong, Hong Kong
Duration: 6 Aug 20148 Aug 2014

Conference

Conference7th Textile Bioengineering and Informatics Symposium, TBIS 2014, in conjunction with the 5th Asian Protective Clothing Conference, APCC 2014
Country/TerritoryHong Kong
CityHong Kong
Period6/08/148/08/14

Keywords

  • Antifungal
  • Athlete's foot
  • Hygienic socks
  • Microcapsules
  • Moisture control

ASJC Scopus subject areas

  • Bioengineering
  • Biomaterials

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