Deformation behavior, corrosion resistance, and cytotoxicity of Ni-free Zr-based bulk metallic glasses

L. Liu, C. L. Qiu, Q. Chen, Kang Cheung Chan, S. M. Zhang

Research output: Journal article publicationJournal articleAcademic researchpeer-review

53 Citations (Scopus)

Abstract

Two Ni-free bulk metallic glasses (BMGs) of Zr60Nb5Cu22.5Pd5Al7.5and Zr60Nb5Cu20Fe5Al10were successfully prepared by arc-melting and copper mold casting. The thermal stability and crystallization were studied using differential scanning calorimetry. It demonstrates that the two BMGs exhibit very good glass forming ability with a wide supercooled liquid region. A multi-step process of crystallization with a preferential formation of quasicrystals occurred in both BMGs under continuous heating. The deformation behavior of the two BMGs was investigated using quasi-static compression testing. It reveals that the BMGs exhibit not only superior strength but also an extended plasticity. Corrosion behaviors of the BMGs were investigated in phosphate buffered solution by electrochemical polarization. The result shows that the two BMGs exhibit excellent corrosion resistance characterized by low corrosion current densities and wide passive regions. X-ray photoelectron spectroscopy analysis revealed that the passive film formed after anodic polarization was highly enriched in zirconium, niobium, and aluminum oxides. This is attributed to the excellent corrosion resistance. Additionally, the potential cytotoxicity of the two Ni-free BMGs was evaluated through cell culture for 1 week followed by 3-(4,5-Dimethylthiazol-2-yl-)-2,5-diphenyltetrazolium bromide assay and SEM observation. The results indicate that the two Ni-free BMGs exhibit as good biocompatibility as Ti-6A1-4V alloy, and thus show a promising potential for biomedical applications.
Original languageEnglish
Pages (from-to)160-169
Number of pages10
JournalJournal of Biomedical Materials Research - Part A
Volume86
Issue number1
DOIs
Publication statusPublished - 1 Jul 2008

Keywords

  • Biocompatibility
  • Corrosion resistance
  • Mechanical properties
  • Ni-free bulk metallic glasses

ASJC Scopus subject areas

  • Ceramics and Composites
  • Biomaterials
  • Biomedical Engineering
  • Metals and Alloys

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