Cortical reorganization for response regulation with unilateral thalamic stroke detected by functional MRI

Kenneth S L Yuen, Tatia M C Lee, Yau Yau Wai, Ho Ling Liu, Edith N H Mok, Leonard S W Li, Che Hin Chan

Research output: Journal article publicationJournal articleAcademic researchpeer-review

3 Citations (Scopus)


To understand neural reorganization of response regulation after stroke, a 54-year-old woman with a chronic left thalamic stroke performed a task requiring decisions about the directionality of an arrow during cerebral functional magnetic resonance imaging. Her performance was compared to 13 matched healthy control subjects. Her behavioral responses were slower but as accurate. Bilateral frontal activations were observed in the right medial frontal gyrus (BA 9), left superior frontal gyrus (BA 45), and left frontal rectus gyrus (BA 11). Activation in the right medial frontal gyrus, along with activity in close proximity to the anterior cingulate cortex, was observed, which may reflect reorganization of activity after the loss of function of the anterior cingulate cortex.
Original languageEnglish
Pages (from-to)467-471
Number of pages5
JournalNeurorehabilitation and Neural Repair
Issue number5
Publication statusPublished - 1 Sep 2007


  • Cortical recovery
  • fMRI
  • Inhibition
  • Neural reorganization
  • Neuroplasticity
  • Response regulation

ASJC Scopus subject areas

  • Rehabilitation
  • Clinical Neurology
  • Neuroscience(all)
  • Health Professions(all)

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