Correspondence between Subjective and Objective Cognitive Functioning Following Chemotherapy for Breast Cancer

Mary E. Mihuta, Heather J. Green, Wai Kwong Man, David H.K. Shum

Research output: Journal article publicationJournal articleAcademic researchpeer-review

4 Citations (Scopus)

Abstract

This study examined subjective and objective cognitive functioning in 26 female breast cancer survivors (BCS) who received chemotherapy treatment that finished.5 to 5 years prior to testing and compared their results to 25 demographically matched women with no history of cancer. Participants were assessed on prospective memory (PM) tasks; neuropsychological tests of processing speed, attentional flexibility with greater cognitive load, executive function, and verbal memory; self-report measures of cognitive dysfunction and PM failures; and distress. The BCS group showed significantly slower speed of processing and reduced attentional flexibility, and reported significantly more cognitive complaints and PM failures than the control group on five of six self-report measures. The groups did not differ on other PM or neuropsychological measures or on a measure of distress. Subjective cognition correlated with some neuropsychological tests and with a virtual reality PM task. Objective cognitive impairments were associated with reduced quality of life in the BCS group. The results provide some evidence of both self-reported impairment and objective cognitive dysfunction following chemotherapy treatment.
Original languageEnglish
Pages (from-to)222-232
Number of pages11
JournalBrain Impairment
Volume17
Issue number3
DOIs
Publication statusPublished - 1 Dec 2016

Keywords

  • Attention/processing speed
  • cancer
  • executive function
  • medical/surgical
  • memory
  • quality of life

ASJC Scopus subject areas

  • Neuropsychology and Physiological Psychology
  • Neurology
  • Clinical Neurology
  • Cognitive Neuroscience
  • Behavioral Neuroscience
  • Speech and Hearing

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