Controllable particle hopping in optofluidic lattice for antibody screening and binding efficiency measurement

Y. Z. Shi, S. Xiong, Y. Zhang, L. K. Chin, J. H. Wu, T. N. Chen, A. Q. Liu

Research output: Chapter in book / Conference proceedingConference article published in proceeding or bookAcademic researchpeer-review

Abstract

Particle patterning and hopping has attracted much attention owing to their extensive involvement in many physical and biological studies. Here, by configuring an intriguing Optofluidic, we are able to pattern 500 nm particles into a 2D array in the flow stream. We also achieve a 2D patterning of cryptosporidium in the microchannel. By investing particle-particle interactions, we studies the long ignored new particle hopping mechanisms, and used them to screen antibodies. Our observed particle hopping in the flow stream completes the family of particle kinetics in optofluidic potential wells and inspires new minds in the develop new light fields in the microchannel. The 2D patterning of particles facilites the parallel culture and study of multiple biological samples in the flow stream.

Original languageEnglish
Title of host publicationOptical Trapping and Optical Micromanipulation XV
EditorsGabriel C. Spalding, Kishan Dholakia
PublisherSPIE
ISBN (Electronic)9781510620179
DOIs
Publication statusPublished - Aug 2018
Externally publishedYes
EventOptical Trapping and Optical Micromanipulation XV 2018 - San Diego, United States
Duration: 19 Aug 201823 Aug 2018

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume10723
ISSN (Print)0277-786X
ISSN (Electronic)1996-756X

Conference

ConferenceOptical Trapping and Optical Micromanipulation XV 2018
Country/TerritoryUnited States
CitySan Diego
Period19/08/1823/08/18

Keywords

  • Antibody screening
  • Optical manipulation
  • Optofluidics
  • Particle hopping

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

Fingerprint

Dive into the research topics of 'Controllable particle hopping in optofluidic lattice for antibody screening and binding efficiency measurement'. Together they form a unique fingerprint.

Cite this