Continuous microfluidic cell/particile separation via combination of electroosmotic and hydrodynamic spreading

Z. G. Wu; Y. F. Yu; A. Q. Liu; P. H. Yap; C. S. Lim; H. M. Hosseini

Continuous microfluidic cell/particile separation via combination of electroosmotic and hydrodynamic spreading

Z. G. Wu, Y. F. Yu, A. Q. Liu, P. H. Yap, C. S. Lim, H. M. Hosseini

Research output: Unpublished conference presentation (presented paper, abstract, poster) › Conference presentation (not published in journal/proceeding/book) › Academic research › peer-review

Abstract

Hydrodynamic spreading separation is an important technique for cells or particles sorting. In this paper, an electroosmotic flow (EOF) and a hydrodynamic flow are combined to control the spreading behavior for continuous cells or particles separation. The hydrodynamic spreading of fluids can be adjusted arbitrary with a tunable applied voltage. This spreading behavior is investigated through numerical simulation and experiment study. Based on the experimental results, particles of two different sizes, 10 and 2 μm, are separated. The experimental results are compared with the numerical results. The suggested technique provides a simple, flexible and versatile way for microfluidic cell sorting.

Original language	English
Pages	1097-1099
Number of pages	3
Publication status	Published - Nov 2006
Externally published	Yes
Event	10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006 - Tokyo, Japan Duration: 5 Nov 2006 → 9 Nov 2006

Conference

Conference	10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006
Country/Territory	Japan
City	Tokyo
Period	5/11/06 → 9/11/06

Keywords

Cell sorting
Electro-osmotic flow
Hydrodynamic spreading
Separation

ASJC Scopus subject areas

Chemical Engineering (miscellaneous)
Bioengineering

Cite this

@conference{1aafbf61adaf4397966924767390e880,

title = "Continuous microfluidic cell/particile separation via combination of electroosmotic and hydrodynamic spreading",

abstract = "Hydrodynamic spreading separation is an important technique for cells or particles sorting. In this paper, an electroosmotic flow (EOF) and a hydrodynamic flow are combined to control the spreading behavior for continuous cells or particles separation. The hydrodynamic spreading of fluids can be adjusted arbitrary with a tunable applied voltage. This spreading behavior is investigated through numerical simulation and experiment study. Based on the experimental results, particles of two different sizes, 10 and 2 μm, are separated. The experimental results are compared with the numerical results. The suggested technique provides a simple, flexible and versatile way for microfluidic cell sorting.",

keywords = "Cell sorting, Electro-osmotic flow, Hydrodynamic spreading, Separation",

author = "Wu, \{Z. G.\} and Yu, \{Y. F.\} and Liu, \{A. Q.\} and Yap, \{P. H.\} and Lim, \{C. S.\} and Hosseini, \{H. M.\}",

year = "2006",

month = nov,

language = "English",

pages = "1097--1099",

note = "10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006 ; Conference date: 05-11-2006 Through 09-11-2006",

}

Continuous microfluidic cell/particile separation via combination of electroosmotic and hydrodynamic spreading. / Wu, Z. G.; Yu, Y. F.; Liu, A. Q. et al.
2006. 1097-1099 Paper presented at 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006, Tokyo, Japan.

Research output: Unpublished conference presentation (presented paper, abstract, poster) › Conference presentation (not published in journal/proceeding/book) › Academic research › peer-review

TY - CONF

T1 - Continuous microfluidic cell/particile separation via combination of electroosmotic and hydrodynamic spreading

AU - Wu, Z. G.

AU - Yu, Y. F.

AU - Liu, A. Q.

AU - Yap, P. H.

AU - Lim, C. S.

AU - Hosseini, H. M.

PY - 2006/11

Y1 - 2006/11

N2 - Hydrodynamic spreading separation is an important technique for cells or particles sorting. In this paper, an electroosmotic flow (EOF) and a hydrodynamic flow are combined to control the spreading behavior for continuous cells or particles separation. The hydrodynamic spreading of fluids can be adjusted arbitrary with a tunable applied voltage. This spreading behavior is investigated through numerical simulation and experiment study. Based on the experimental results, particles of two different sizes, 10 and 2 μm, are separated. The experimental results are compared with the numerical results. The suggested technique provides a simple, flexible and versatile way for microfluidic cell sorting.

AB - Hydrodynamic spreading separation is an important technique for cells or particles sorting. In this paper, an electroosmotic flow (EOF) and a hydrodynamic flow are combined to control the spreading behavior for continuous cells or particles separation. The hydrodynamic spreading of fluids can be adjusted arbitrary with a tunable applied voltage. This spreading behavior is investigated through numerical simulation and experiment study. Based on the experimental results, particles of two different sizes, 10 and 2 μm, are separated. The experimental results are compared with the numerical results. The suggested technique provides a simple, flexible and versatile way for microfluidic cell sorting.

KW - Cell sorting

KW - Electro-osmotic flow

KW - Hydrodynamic spreading

KW - Separation

UR - http://www.scopus.com/inward/record.url?scp=84902504682&partnerID=8YFLogxK

M3 - Conference presentation (not published in journal/proceeding/book)

AN - SCOPUS:84902504682

SP - 1097

EP - 1099

T2 - 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006

Y2 - 5 November 2006 through 9 November 2006

ER -

Continuous microfluidic cell/particile separation via combination of electroosmotic and hydrodynamic spreading

Abstract

Conference

Keywords

ASJC Scopus subject areas

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