Construction of nonbiofouling biofunctional glass surface by self-assembled monolayer and graft hydrophilic polymer

Zongbin Liu, Bei Zhang, Brian Yu Fung Pow, Mo Yang, Arthur Fuk Tak Mak

Research output: Chapter in book / Conference proceedingConference article published in proceeding or bookAcademic researchpeer-review

2 Citations (Scopus)

Abstract

This paper introduces a new method of surface modification by self-assembled monolayer (SAM) and polymer monolayer grafting. Since most of the glass surfaces lack the reactive functional group, an activation process with 3-(trimethoxysilyl)propyl methacrylate(TPM) is used in our experiment to generate the vinyl reactive sites on the substrate surface for further graft polymerization. The TPM saline layer acts as the "anchor" part to link the functional part onto the surface of substrate. The paper summarizes the surface modifications by the polymerizations of PEGMA, AA(Acrylic acid) and NVP(Nitrogen-vinyl-2-pyrrolidone) respectively and their applications for protein adsorption and cell adhesion through a series of measurements. In previous research, AA and NVP had also been adopted for surface treatment and had achieved good results. The substrate can be glass, alumina, silicon, metals or stainless steel. We choose glass as our substrate during the experiment.
Original languageEnglish
Title of host publicationMulti-functional Materials and Structures - International Conference on Multifunctional Materials and Structures
PublisherTrans Tech Publications
Pages1343-1346
Number of pages4
ISBN (Print)0878493786, 9780878493784
Publication statusPublished - 1 Jan 2008
EventMulti-functional Materials and Structures - International Conference on Multifunctional Materials and Structures - Hong Kong, P.R., Hong Kong
Duration: 28 Jul 200831 Jul 2008

Publication series

NameAdvanced Materials Research
Volume47-50 PART 2
ISSN (Print)1022-6680

Conference

ConferenceMulti-functional Materials and Structures - International Conference on Multifunctional Materials and Structures
Country/TerritoryHong Kong
CityHong Kong, P.R.
Period28/07/0831/07/08

Keywords

  • Protein adsorption
  • Self-assembled monolayer
  • Surface modification

ASJC Scopus subject areas

  • Engineering(all)

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