TY - GEN
T1 - Construction of nonbiofouling biofunctional glass surface by self-assembled monolayer and graft hydrophilic polymer
AU - Liu, Zongbin
AU - Zhang, Bei
AU - Pow, Brian Yu Fung
AU - Yang, Mo
AU - Mak, Arthur Fuk Tak
PY - 2008/1/1
Y1 - 2008/1/1
N2 - This paper introduces a new method of surface modification by self-assembled monolayer (SAM) and polymer monolayer grafting. Since most of the glass surfaces lack the reactive functional group, an activation process with 3-(trimethoxysilyl)propyl methacrylate(TPM) is used in our experiment to generate the vinyl reactive sites on the substrate surface for further graft polymerization. The TPM saline layer acts as the "anchor" part to link the functional part onto the surface of substrate. The paper summarizes the surface modifications by the polymerizations of PEGMA, AA(Acrylic acid) and NVP(Nitrogen-vinyl-2-pyrrolidone) respectively and their applications for protein adsorption and cell adhesion through a series of measurements. In previous research, AA and NVP had also been adopted for surface treatment and had achieved good results. The substrate can be glass, alumina, silicon, metals or stainless steel. We choose glass as our substrate during the experiment.
AB - This paper introduces a new method of surface modification by self-assembled monolayer (SAM) and polymer monolayer grafting. Since most of the glass surfaces lack the reactive functional group, an activation process with 3-(trimethoxysilyl)propyl methacrylate(TPM) is used in our experiment to generate the vinyl reactive sites on the substrate surface for further graft polymerization. The TPM saline layer acts as the "anchor" part to link the functional part onto the surface of substrate. The paper summarizes the surface modifications by the polymerizations of PEGMA, AA(Acrylic acid) and NVP(Nitrogen-vinyl-2-pyrrolidone) respectively and their applications for protein adsorption and cell adhesion through a series of measurements. In previous research, AA and NVP had also been adopted for surface treatment and had achieved good results. The substrate can be glass, alumina, silicon, metals or stainless steel. We choose glass as our substrate during the experiment.
KW - Protein adsorption
KW - Self-assembled monolayer
KW - Surface modification
UR - http://www.scopus.com/inward/record.url?scp=56349160790&partnerID=8YFLogxK
M3 - Conference article published in proceeding or book
SN - 0878493786
SN - 9780878493784
T3 - Advanced Materials Research
SP - 1343
EP - 1346
BT - Multi-functional Materials and Structures - International Conference on Multifunctional Materials and Structures
PB - Trans Tech Publications
T2 - Multi-functional Materials and Structures - International Conference on Multifunctional Materials and Structures
Y2 - 28 July 2008 through 31 July 2008
ER -