Computational modeling of fluid-structure interaction between blood flow and mitral valve

Weixin Si, Xiangyun Liao, Jing Qin, Pheng Ann Heng

Research output: Chapter in book / Conference proceedingChapter in an edited book (as author)Academic researchpeer-review


Mitral valve repair is a complex operation, in which the functionality of incompetent mitral valve is reconstructed by surgical techniques. Simulation-based surgical planning system, allowing surgeons to simulate and compare potential repair strategies, could greatly improve surgical outcomes. This paper presents a practical computational framework, combining the Total Lagrangian Explicit Dynamics Finite Element Method (TLED FEM) and Smoothed Particle Hydrodynamics (SPH), to solve the interaction problem of blood and immersed mitral valves. With this completed pipeline, we can not only predict the mechanical behavior of mitral valve, but also analyze the transvalvular pressures distributed on valve leaflets. The experimental results demonstrate that our method has the potential to be applied in surgical planning simulator of mitral valve repair.

Original languageEnglish
Title of host publicationComputational Biomechanics for Medicine
Subtitle of host publicationMeasurements, Models, and Predictions
PublisherSpringer International Publishing
Number of pages11
ISBN (Electronic)9783319755892
ISBN (Print)9783319755885
Publication statusPublished - 14 May 2018

ASJC Scopus subject areas

  • Engineering(all)
  • Computer Science(all)
  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Physics and Astronomy(all)

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