Computation of uniaxial modulus of the normal and degenerated articular cartilage using inhomogeneous triphasic model

Haijun Niu, Qing Wang, Yongping Zheng, Fang Pu, Yubo Fan, Deyu Li

Research output: Chapter in book / Conference proceedingConference article published in proceeding or bookAcademic researchpeer-review

1 Citation (Scopus)


Articular cartilage is a biological weight-bearing tissue covering the bony ends of articulating joints. Subtle changes in tissue composition can lead to degeneration of articular cartilage. This study develops an improved inhomogeneous triphasic model with four parameters and extracts the uniaxial modulus (Ha) for both normal and degenerated articular cartilage, and then predicts the swelling pattern of the cartilage. The results indicated that the new inhomogeneous triphasic model can extract uniaxial modulus more accurately, and the predict results also appeared to well match the experimental strain data. This inhomogeneous triphasic model can describe the depth-dependent material attribute of normal and degenerated articular cartilage more exactly.
Original languageEnglish
Title of host publicationLife System Modeling and Simulation - International Conference, LSMS 2007, Proceedings
Number of pages7
Publication statusPublished - 1 Dec 2007
Event2007 International Conference on Life System Modeling and Simulation, LSMS 2007 - Shanghai, China
Duration: 14 Sep 200717 Sep 2007

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume4689 LNBI
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349


Conference2007 International Conference on Life System Modeling and Simulation, LSMS 2007

ASJC Scopus subject areas

  • Theoretical Computer Science
  • Computer Science(all)

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