Comprehensive Review of COVID-19: Epidemiology, Pathogenesis, Advancement in Diagnostic and Detection Techniques, and Post-Pandemic Treatment Strategies

Yiu Sing Chung, Ching Yin Lam, Pak Hei Tan, Hin Fung Tsang, Sze Chuen Cesar Wong

Research output: Journal article publicationReview articleAcademic researchpeer-review

12 Citations (Scopus)

Abstract

At present, COVID-19 remains a public health concern due to the ongoing evolution of SARS-CoV-2 and its prevalence in particular countries. This paper provides an updated overview of the epidemiology and pathogenesis of COVID-19, with a focus on the emergence of SARS-CoV-2 variants and the phenomenon known as ‘long COVID’. Meanwhile, diagnostic and detection advances will be mentioned. Though many inventions have been made to combat the COVID-19 pandemic, some outstanding ones include multiplex RT-PCR, which can be used for accurate diagnosis of SARS-CoV-2 infection. ELISA-based antigen tests also appear to be potential diagnostic tools to be available in the future. This paper also discusses current treatments, vaccination strategies, as well as emerging cell-based therapies for SARS-CoV-2 infection. The ongoing evolution of SARS-CoV-2 underscores the necessity for us to continuously update scientific understanding and treatments for it.

Original languageEnglish
Article number8155
JournalInternational Journal of Molecular Sciences
Volume25
Issue number15
DOIs
Publication statusPublished - 26 Jul 2024

Keywords

  • COVID-19
  • endemic
  • post-pandemic
  • review
  • SARS-CoV-2

ASJC Scopus subject areas

  • Catalysis
  • Molecular Biology
  • Spectroscopy
  • Computer Science Applications
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

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